Alveolar type 2 epithelial cell organoids: focus on culture methods
… ” or “alveolar organoid”. We screened articles focused on alveolar organoid cultures and
their applications. Then, we categorized studies based on the sources of cells, matrix, culture …
their applications. Then, we categorized studies based on the sources of cells, matrix, culture …
Dissecting the niche for alveolar type II cells with alveolar organoids
D Liao, H Li - Frontiers in Cell and Developmental Biology, 2020 - frontiersin.org
… cells within this type of organoids exhibit overlapped signals of SPC and AQP5 (the marker
for AEC1 cell… , we propose that alveolar organoids that are similar in structure to alveoli of the …
for AEC1 cell… , we propose that alveolar organoids that are similar in structure to alveoli of the …
Organoid-based expansion of patient-derived primary alveolar type 2 cells for establishment of alveolus epithelial Lung-Chip cultures
S van Riet, A van Schadewijk… - … -Lung Cellular and …, 2022 - journals.physiology.org
… alveolar microenvironment. To test the feasibility of such a model, we isolated primary alveolar
type 2 cells (… selection of cells expressing the AEC2 marker HTII-280. We obtained pure …
type 2 cells (… selection of cells expressing the AEC2 marker HTII-280. We obtained pure …
An organoid‐derived bronchioalveolar model for SARS‐CoV‐2 infection of human alveolar type II‐like cells
… , bronchioalveolar‐like cells derived from self‐renewing human fetal lung organoids give rise
… , alveolar type II‐like cells are permissive to SARS‐CoV‐2 infection, which induces a type I/…
… , alveolar type II‐like cells are permissive to SARS‐CoV‐2 infection, which induces a type I/…
Plasticity of Hopx+ type I alveolar cells to regenerate type II cells in the lung
R Jain, CE Barkauskas, N Takeda, EJ Bowie… - Nature …, 2015 - nature.com
… that Hopx becomes restricted to type I cells in the adult alveolus and is excluded from type II,
Sftpc + cells (Fig. 2h). … (e–h) Type II cell organoids grown in the presence of LY also contain …
Sftpc + cells (Fig. 2h). … (e–h) Type II cell organoids grown in the presence of LY also contain …
Human alveolar progenitors generate dual lineage bronchioalveolar organoids
K Hoffmann, B Obermayer, K Hönzke… - Communications …, 2022 - nature.com
… from alveolar type 2 (AT2) precursors to alveolar type 1 (AT1) terminally differentiated … the
potency to generate organoids with both alveolar and bronchial cell types. In vitro induction …
potency to generate organoids with both alveolar and bronchial cell types. In vitro induction …
Long-term expansion of alveolar stem cells derived from human iPS cells in organoids
… Alveolar epithelial type II (AT2) cells function as tissue stem … of alveolar organoids (AOs)
harboring SFTPC + alveolar stem cells derived from human induced pluripotent stem cells (…
harboring SFTPC + alveolar stem cells derived from human induced pluripotent stem cells (…
Modeling diverse genetic subtypes of lung adenocarcinoma with a next-generation alveolar type 2 organoid platform
S Naranjo, CM Cabana, LM LaFave… - Genes & …, 2022 - genesdev.cshlp.org
… However, robust and faithful LUAD organoid platforms are currently lacking. Here, we …
murine alveolar type 2 (AT2) cells, a prominent cell of origin for LUAD, in organoid culture. These …
murine alveolar type 2 (AT2) cells, a prominent cell of origin for LUAD, in organoid culture. These …
Alveolar wars: the rise of in vitro models to understand human lung alveolar maintenance, regeneration, and disease
KV Evans, JH Lee - Stem Cells Translational Medicine, 2020 - academic.oup.com
… of alveolar cells, including alveolar type II stem/progenitor cells, … , cellular diversity, and
previously unknown cell types, some … analysis of alveolar cells, in vitro human alveolar organoids …
previously unknown cell types, some … analysis of alveolar cells, in vitro human alveolar organoids …
Establishment of a three-dimensional organoid culture system for mouse type 2 alveolar epithelial cells
J Wei, CF Xu, XY Zhu, YJ Liu - Sheng li xue bao:[Acta Physiologica …, 2022 - europepmc.org
… (3D) organoid culture system for type 2 alveolar epithelial (AT2) cells in mice. AT2 … Some
of the proSPC-positive AT2 cells located in the outer circle of alveolar organoids were stained …
of the proSPC-positive AT2 cells located in the outer circle of alveolar organoids were stained …
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