Alzheimer’s disease (AD) is characterized neuropathologically by the deposition of different
forms of amyloid β-protein (Aβ) including variable amounts of soluble species that correlate …

… Alzheimer's disease (AD) has made great strides over the last decade. This progress is the
result of protein … during the 1980s, which identified β‐amyloid protein (Aβ) and tau as their …

Alzheimer's disease is a devastating disorder that … , disease-modifying, or curative therapies.
Substantial evidence indicates that the amyloid β-protein (Aβ) is a seminal factor in disease …

Alzheimer’s disease (AD) is characterized by the deposition of amyloid in the extracellular
compartment of the brain in the form of congophilic amyloid angiopathy (CAA) and amyloid …

A major histopathological hallmark of Alzheimer's disease (AD) is the presence of amyloid
deposits in the parenchyma of the amygdala, hippocampus, and neocortex. The principal …

The effort to decipher the mechanism of Alzheimer’s disease (AD) 1 has attracted the interest
of investigators from diverse biological disciplines, including biochemistry, cell biology, …

Publisher Summary This chapter reviews the emerging understanding of the causes and
mechanism of Alzheimer's disease (AD) that has developed and what it is ultimately likely to …

Alzheimer's disease (AD) is characterized by amyloid deposits within the neocortical parenchyma
and the cerebrovasculature. The main component of these predominantly extracellular …

… We conclude that further deep molecular analyses of the disease, including the mechanisms
of β-amyloidosis, will enable more effective clinical trials and ultimately achieve the …

Alzheimer’s disease (AD) is an age-related neurodegenerative disease characterized
clinically by cognitive decline and pathologically by the accumulation of amyloid-β-containing …