… Herein, we will provide a brief overview of AD and the involvement of apoptosis in disease
pathogenesis. In addition, we will review the potential role of bile acids as modulators of …

… into the bile and transported to the gut lumen when they are metabolized by bacteria. Gut
microbiota initiates bile acid metabolism via a critical first step catalyzed by bile salt hydrolases …

… Bile acid synthesis and cholesterol clearance pathway. Regulation of bile acid synthesis by
feedback mechanism and bile acid … BSEP and canalicular bile acid secretion. In the intestine, …

… that bile acids (BAs) are involved in the onset and progression of neurological and
neuropsychiatric diseases… of brain diseases, depression, Alzheimer disease (AD), and stroke [22, …

… of bile acids are clearly disturbed during the development of AD pathology and, since some
bile acids are … a method that can be used to support work to advance bile acid therapeutics. …

… Bile acids and their ratios reflective of gut microbiome and liver enzymatic activities and …
for Alzheimer's disease. Heat map of q-values of association between bile acid profiles and the “…

… and bile acid metabolism linked to Alzheimer disease (AD) Evidence for alternative bile acid
… and identify genes in the alternative bile acid synthesis pathway to be expressed in the brain…

… Bile Acid kit from Biocrates to analyze 20 bile acid metabolites. Our data will reveal that
plasma levels of the bile acid lithocholic acid (… during stages of Alzheimers disease are lacking. …

… include bile acids and steroid hormones. Intermediates in the bile acid biosynthesis … ], [27],
[28] and brain [29], [30], while bile acids have been found in rodent [29], [31], [32] and …

… neurologic diseases [20,21]. Recent studies also suggest primary and secondary bile acids
… We have also reported an altered brain and serum bile acid profile in the App NL-GF mouse …