… Alzheimer's disease (AD) is a chronic neurodegenerative disorder characterized by the …
brain inflammation, which promotes disease pathogenesis. In this context, the blood-brain barrier …

… blood-brain barrier play a role in the development of cerebral amyloidosis and Alzheimer's
disease … Amyloid-β peptide as a vaccine for Alzheimer's disease involves receptor-mediated …

… diseases of the CNS, such as multiple sclerosis and AD, changes in blood composition,
brain inflammation and the facilitated entrance of immune cells through the brain barriers can …

… between the blood flow and brain parenchyma, thereby … diseases, including Alzheimer’s
disease (AD). While amyloid-β (Aβ) deposition and neurofibrillary tangle formation in the brain …

The blood–brain barrier (BBB) plays critical roles in the maintenance of central nervous
system (CNS) homeostasis. Dysfunction of the BBB occurs in a number of CNS diseases, …

Alzheimer’s disease (AD) is the most common form of dementia, affecting millions of people
worldwide. One of the prominent causative factors of AD pathogenesis is cerebral vascular …

… is relevant to Alzheimer's disease with examples. Endothelial cell #1: Dysfunctions of BBB
can promote AD as exemplified here by impaired efflux of A-beta from brain. Endothelial cell #…

… pathogens out of the brain. An early BBB breakdown and/or dysfunction have been shown
in Alzheimer’s disease (AD) before dementia, neurodegeneration and/or brain atrophy occur. …

… was moderate athersosclerosis in the basal brain arteries of Auguste D provide a … of Alzheimer,
which we use today to define AD. Nevertheless, it remains to be known whether the brain …

… The blood-brain barrier (BBB) is involved in the pathogenesis of Alzheimer’s disease (AD). …
internal environment of the brain and prevents foreign objects invading the brain tissue. BBB …