Genome-wide DNA methylation differences between late-onset Alzheimer's disease and cognitively normal controls in human frontal cortex

KM Bakulski, DC Dolinoy, MA Sartor… - … of Alzheimer's …, 2012 - content.iospress.com
… in AD pathogenesis or identified through GWAS for genetic association with LOAD were
largely not associated with disease-specific DNA methylation differences in this study. A notable …

Distinct sex-specific DNA methylation differences in Alzheimer's disease

T C. Silva, W Zhang, JI Young, L Gomez… - Alzheimer's research & …, 2022 - Springer
DNA methylation differences in AD are largely distinct between males and females. Our
best-performing sex-specific methylation-… of AD samples with our methylation-based prediction …

Sex-specific DNA methylation differences in Alzheimer's disease pathology

L Zhang, JI Young, L Gomez, TC Silva… - Acta neuropathologica …, 2021 - Springer
… of the sex-specific DNA methylation differences, we next compared them with targets of drugs
in the ChEMBL database [48] that are annotated to Alzheimer's disease, many of which are …

Harnessing peripheral DNA methylation differences in the Alzheimer's Disease Neuroimaging Initiative (ADNI) to reveal novel biomarkers of disease

…, Alzheimer's Disease Neuroimaging Initiative (ADNI) - Clinical …, 2020 - Springer
… differential peripheral DNA methylation in a cohort of AD, MCI, and age-matched CN individuals
with longitudinal DNA methylation measurements. Epigenome-wide association studies …

DNA methylation in Alzheimer's disease: In brain and peripheral blood

X Wei, L Zhang, Y Zeng - Mechanisms of Ageing and Development, 2020 - Elsevier
Alzheimer's disease (AD) is the most widespread … DNA methylation is a vital component of
the epigenetic … Studies of DNA methylation have been proceeded in different brain samples, …

[PDF][PDF] DNA methylation alterations in Alzheimer's disease

AS Yokoyama, JC Rutledge… - Environmental epigenetics, 2017 - academic.oup.com
DNA methylation differences. In studies on DNA methylation in AD, global DNA methylation
is … Folate, vitamin B12, and serum total homocysteine levels in confirmed Alzheimer disease. …

Epigenome-wide meta-analysis of DNA methylation differences in prefrontal cortex implicates the immune processes in Alzheimer's disease

L Zhang, TC Silva, JI Young, L Gomez… - Nature …, 2020 - nature.com
… Therefore, methylation differences at individual CpGs and … Our final set of DNA methylation
differences included these … methylation differences were hyper-methylated in AD, for which …

Dynamics of DNA methylation in aging and Alzheimer's disease

HA Irier, P Jin - DNA and cell biology, 2012 - liebertpub.com
… Exact levels of 5hmC in genomic DNA vary among the different tissue types in different
variability is due to the different detection methods used by different laboratories remains to be …

Global changes in DNA methylation and hydroxymethylation in Alzheimer's disease human brain

N Coppieters, BV Dieriks, C Lill, RLM Faull… - Neurobiology of …, 2014 - Elsevier
… (5-methylcytosine [5mC]) is one of several epigenetic markers altered in Alzheimer's disease
(… Genome-wide DNA methylation differences between late-onset Alzheimer's disease and …

Epigenetic changes in Alzheimer's disease: decrements in DNA methylation

D Mastroeni, A Grover, E Delvaux, C Whiteside… - Neurobiology of …, 2010 - Elsevier
… of DNA methylation and eight methylation maintenance factors in entorhinal cortex layer II, a
region exhibiting substantial Alzheimer's disease (… implicated in many different modalities of …