… emerging now for Alzheimer’s disease. The … drug discovery and drug development. Investors
are quite wary of investing in early stage drug discovery, especially for Alzheimer’s disease, …

… to barriers to drug discovery in academia are generic problems in academia, we believe
that the approach to facilitating drug discovery and development should be disease specific. …

… tissue is one of the hallmarks of Alzheimer’s disease (2). This … in the brains of patients with
Alzheimer’s disease (4). Kinetic … effective drug discovery strategy against Alzheimer’s disease…

… to neurodegenerative disease drug discovery is likely to produce safe and effective drugs. …
been developed, and the overall rate of drug discovery has greatly decreased over the last 10 …

… , drug discovery in a high-throughput scale can be achieved using this model system 155 .
Till date, very few studies involving neurological drug discovery … effect of these drugs is similar …

… pressure on drug discovery efforts to identify innovative therapies for Alzheimer's disease (…
can supplement, expand and improve transgenic mouse models used in AD drug discovery. …

… and LightGBM in the drug discovery process for AChE inhibitors in Alzheimer's disease. The
… -activity relationships and facilitating the drug discovery process for Alzheimer's disease. …

… , and to prove that any drug target is valuable in AD, disease-relevant models giving insight
… a promising novel tool for disease modelling and drug discovery for the sporadic form of AD. …

… Valid animal models are indispensable to the drug discovery and development pipeline. In
… discovery and validation, which require proof that a molecular target is pivotal to a disease …

… that are subsequently responsible for neuronal death in Alzheimer’s disease (AD). However,
recent … Aβ42 as a novel strategy for AD drug discovery. Drug Dev. Res 55:194–200, 2002. …