… This review summarizes pioneering efforts in mechanisms of disease and novel drug
targets for Alzheimer′s disease research. We would like to emphasize the importance of …

… disease (source: Alzheimer’s Association, Chicago). We will briefly review the current state of
knowledge in Alzheimer’… to the development of new potential drug targets for AD treatment. …

… , and acts as catalyst for Aβ aggregation in Alzheimer's disease (AD). Thus, disruption of
aberrant … promise as a rational therapeutic strategy against Alzheimer's amyloid pathogenesis. …

… the basis for devising better drug targets, strategies for diagnosis, prevention and treatment.
… Overall, this current research should lead to the development of new potential drug targets …

… Accordingly, we sought to discover promising drug targets for AD by combining high-throughput
proteomics in the brain and blood with genetic data to determine the genomic …

Alzheimer’s disease (AD) is a chronic neurodegenerative disease affecting the elderly. AD is
associated with a progressive decline in memory and cognitive abilities, drastic changes in …

… in Alzheimer’s disease … target the cause of the disease rather than the symptoms. This
review describes the inflammatory pathways that are thought to be present in Alzheimer’s disease …

… Alzheimer’s disease, their potential as targets for pharmacological intervention has only
recently been investigated. In the last few years, the Alzheimer … etiology of Alzheimer’s disease, …

Accumulation of β-amyloid peptide (Aβ) in the brain regions responsible for memory and
cognitive functions is a neuropathological hallmark of Alzheimer’s disease. Cholesterol may be …

… Inhibition of the formation of toxic Aβ and pTau aggregates has been an old drug target. …
for AD treatments if the disease is detected at early stages. More recently, novel targets, eg, …