Brain ischemia and ischemic blood–brain barrier as etiological factors in sporadic Alzheimer's disease

R Pluta, MU Amek - Neuropsychiatric disease and treatment, 2008 - Taylor & Francis
… supports the role of ischemia in neuronal death and ischemic blood–brain barrier in
amyloid plaques development in Alzheimer’s disease etiology. Influence of ischemia and β-amyloid …

Role of ischemic blood-brain barrier on amyloid plaques development in Alzheimer's disease brain

R Pluta - Current neurovascular research, 2007 - ingentaconnect.com
… demonstrated that ischemic brain injury induces chronic changes in blood-brain … Alzheimer’s
disease. This review presented chronic micro-blood-brain barrier openings in ischemic gray …

Is the ischemic blood–brain barrier insufficiency responsible for full-blown Alzheimer's disease?

R Pluta - Neurological research, 2006 - Taylor & Francis
… of both diseases and try to … of Alzheimer’s disease involves an initial ischemic neuronal
alterations leading to enhanced neuronal vulnerability to bamyloid peptide and the ischemic

Cerebral blood flow in ischemic vascular dementia and Alzheimer's disease, measured by arterial spin-labeling magnetic resonance imaging

N Schuff, S Matsumoto, J Kmiecik, C Studholme… - Alzheimer's & …, 2009 - Elsevier
… subcortical ischemic vascular dementia (SIVD) and Alzheimer's disease (AD) on cerebral
blood … and subcortical vascular disease, measured as volume of white-matter lesions (WMLs). …

Primary cerebral blood flow deficiency and Alzheimer's disease: shadows and lights

M Mazza, G Marano, G Traversi… - … Alzheimer's Disease, 2011 - content.iospress.com
… So we can describe combined mechanisms of ischemia processes, ischemic and chronic
BBB dysfunction, and Aß peptide-dependent injury in pathology of neurodegeneration that is …

post-ischemic permeability of the blood–brain barrier to amyloid and platelets as a factor in the maturation of Alzheimer's Disease-type brain neurodegeneration

R Pluta, B Miziak, SJ Czuczwar - International Journal of Molecular …, 2023 - mdpi.com
… of the impact of ischemic changes in the blood–brain barrier on the maturation of post-ischemic
brain neurodegeneration with features of Alzheimer’s disease. Understanding the …

Sporadic Alzheimer's disease begins as episodes of brain ischemia and ischemically dysregulated Alzheimer's disease genes

R Pluta, M Jabłoński, M Ułamek-Kozioł, J Kocki… - Molecular …, 2013 - Springer
… were noted in blood [39–41]. The presented data will strongly underpin hypothesis that brain
ischemia is involved in the etiology of sporadic Alzheimer’s disease. Potential contribution …

Alzheimer's mechanisms in ischemic brain degeneration

R Pluta, M Ułamek, M Jabłoński - The Anatomical Record …, 2009 - Wiley Online Library
… between ischemic injury dementia and Alzheimer's disease … stroke and during Alzheimer's
disease is neuroinflammation, … the blood-brain barrier after ischemia (10-min brain ischemia, 6 …

Alterations of the blood-brain barrier and glial cells in white-matter lesions in cerebrovascular and Alzheimer's disease patients

H Tomimoto, I Akiguchi, T Suenaga, M Nishimura… - Stroke, 1996 - Am Heart Assoc
… We selected and examined 14 brains with ischemic CVD, 12 brains with AD, and 6 control
… for Alzheimer's Disease diagnostic neuropathologic criteria. The cases with ischemic CVD …

The blood brain barrier in Alzheimer's disease

A Chakraborty, NM De Wit, WM Van Der Flier… - Vascular …, 2017 - Elsevier
… Loss or depletion of blood flow during ischemia and/or inflammation insults the brain …
Enhanced microvascular permeability is one of the major after-effects of hypoxia or ischemia. …