Mapping of a gene predisposing to early–onset Alzheimer's disease to chromosome 14q24. 3
C Van Broeckhoven, H Backhovens, M Cruts… - Nature …, 1992 - nature.com
… the genetic map positions of STR markers and AACT**. Although AACT was not included
in the genetic linkage map, we have put it next to the Pl gene since both these genes are …
in the genetic linkage map, we have put it next to the Pl gene since both these genes are …
The genetic defect causing familial Alzheimer's disease maps on chromosome 21
PH St George-Hyslop, RE Tanzi, RJ Polinsky… - Science, 1987 - science.org
… disease, adult polycystic kidney disease, and cystic fibrosis, as well as several X-linked
disorders (9). We have applied the strategy of genetic … the FAD gene does map to chromosome …
disorders (9). We have applied the strategy of genetic … the FAD gene does map to chromosome …
A brief history of Alzheimer's disease gene discovery
RE Tanzi - Journal of Alzheimer's disease, 2013 - content.iospress.com
… (RFLPs) comprising our full genetic linkage map of chromosome 21. Our AD linkage results
for all RFLPs spanning our chromosome 21 genetic linkage map were entirely negative for …
for all RFLPs spanning our chromosome 21 genetic linkage map were entirely negative for …
Genome-wide meta-analysis, fine-mapping and integrative prioritization implicate new Alzheimer's disease risk genes
J Schwartzentruber, S Cooper, JZ Liu… - Nature …, 2021 - nature.com
… gene expression, which probably occurs in a cell-type-dependent manner. A growing number
of studies have mapped genetic variants affecting gene … putative causal genetic variants …
of studies have mapped genetic variants affecting gene … putative causal genetic variants …
Mapping the gene network landscape of Alzheimer's disease through integrating genomics and transcriptomics
… processes, and is impacted significantly by genetic factors. Through integration of the … a
disease gene network that includes a total of 788 genes, and annotated 17 major gene clusters …
disease gene network that includes a total of 788 genes, and annotated 17 major gene clusters …
DNA methylation map of mouse and human brain identifies target genes in Alzheimer's disease
… models of Alzheimer’s disease. We were able to translate these findings to patients with
Alzheimer’s disease, identifying DNA methylation-associated silencing of three targets genes: …
Alzheimer’s disease, identifying DNA methylation-associated silencing of three targets genes: …
Mapping the genetic landscape of early-onset Alzheimer's disease in a cohort of 36 families
MO Mol, SJ van der Lee, M Hulsman… - Alzheimer's Research & …, 2022 - Springer
Background Many families with clinical early-onset Alzheimer’s disease (EOAD) remain
genetically unexplained. A combination of genetic factors is not standardly investigated. In …
genetically unexplained. A combination of genetic factors is not standardly investigated. In …
Gene identification in Alzheimer's disease
AM Saunders - Pharmacogenomics, 2001 - Taylor & Francis
… One outcome of identifying genetically relevant disease genes and mapping the human
genome’s SNPs will be the ability to help predict and improve a patient’s response to a medicine …
genome’s SNPs will be the ability to help predict and improve a patient’s response to a medicine …
AD gene 3-D: moving past single layer genetic information to map novel loci involved in Alzheimer's disease
AJ Myers - Journal of Alzheimer's disease, 2012 - journals.sagepub.com
… The standard approach to mapping genes of interest in Alzheimer’s disease (AD) has … Prior
to the sequencing of the human genome, the main method for gene mapping involved family-…
to the sequencing of the human genome, the main method for gene mapping involved family-…
Identification of risk genes for Alzheimer's disease by gene embedding
Y Lagisetty, T Bourquard, I Al-Ramahi, CG Mangleburg… - Cell genomics, 2022 - cell.com
… -gene interactions, even though these play a crucial role in complex, polygenic diseases
like Alzheimer’s disease (AD). To discover new genes whose interactions may contribute to …
like Alzheimer’s disease (AD). To discover new genes whose interactions may contribute to …
相关搜索
- alzheimer's disease maps genetic defect
- alzheimer's disease dna methylation
- molecular genetics of alzheimer's disease
- alzheimer disease genetic studies
- alzheimer's disease candidate genes
- familial alzheimer's disease locus
- alzheimer's disease down syndrome
- alzheimer's disease brain regions
- alzheimer's disease chromosome 14q24
- alzheimer's disease risk genes fine mapping
- genetic etiology of alzheimer's disease
- genetic heterogeneity of alzheimer's disease
- genetic underpinnings in alzheimer's disease
- genome variants alzheimer's disease genes
- integration of alzheimer's disease genetics
- genetic evidence alzheimer's disease locus