… , we postulate that tau can initiate neurovascular pathology in AD through mitochondrial …
tau pathology contribution to the malfunction of the brain vasculature and neurovascular unit, …

… 79,80,81 — showed greater regional CBF decline in brain regions that are particularly
vulnerable to pathological changes in Alzheimer's disease than did people without this allele 82 . …

… the constituent cells of the neurovascular unit – particularly of … images from the Alzheimer's
Disease Neuroimaging Initiative … an early and possibly an initial pathological event in AD [17, …

… cell cycle, a pathologic feature of AD, is prevented but not reversed by NSAIDs, suggesting
that inflammation is important for initiation but not the progression of the disease process [88]. …

… Pathway 3 leads to Alzheimer’s disease pathology with … of cortical microvascular pathology
in aging and Alzheimer’s … gene in neurovascular dysfunction in Alzheimer disease. Nat …

… Subsequently, we will analyze the vascular amyloid accumulation as well as dysfunction
in both the neurovascular unit (NVU) and the blood–brain barrier (BBB) as early pathological …

… 1) is a major pathological insult to the neurovascular unit in AD [85]. Aβ plaques also
accumulate onto and around cerebral capillaries [16, 92]. Decreased clearance of Aβ across the …

… view is that cerebrovascular dysregulation is a feature not only of cerebrovascular pathologies,
such as stroke, but also of neurodegenerative conditions, such as Alzheimer's disease. …

… cerebral pathologies and neurological disorders. This review will focus on the neurophysiology
of neurovascular … disease may affect the regulation of CBF and neurovascular coupling. …

… in the prevention of neurovascular dysfunction and other pathological processes in AD. …
], this could be relevant to neurovascular dysfunction and the heightened AD risk conferred …