[HTML][HTML] Exploring biomarkers for Alzheimer's disease

N Sharma, AN Singh - Journal of clinical and diagnostic research …, 2016 - ncbi.nlm.nih.gov
… enough, since the plasma levels are largely affected by … in blood plasma, to be crucial potential
AD biomarkers for future … blood plasma to be a highly sensitive and specific biomarker for …

Blood-based biomarkers for Alzheimer's disease: plasma Aβ40 and Aβ42, and genetic variants

R Mayeux, N Schupf - Neurobiology of aging, 2011 - Elsevier
… several plasma biomarkers but most frequently plasma amyloid … use of genetic variants as
biomarkers for diagnosis or risk. … regarding plasma Aβ40 and Aβ42 as diagnostic biomarkers

The discovery and early validation of novel plasma biomarkers in mild-to-moderate Alzheimer's disease patients responding to treatment with rosiglitazone

EL Akuffo, JB Davis, SM Fox, IS Gloger, D Hosford… - Biomarkers, 2008 - Taylor & Francis
… This has highlighted the need for reliable and convenient biomarkers for both early disease
biomarkers in patients with Alzheimer's disease and the correlation of those biomarkers with …

The development of effective biomarkers for Alzheimer's disease: a review

MS Henry, AP Passmore, S Todd… - … journal of geriatric …, 2013 - Wiley Online Library
… of CSF biomarkers is limited by the invasive nature of lumbar puncture. Plasma biomarkers
require only peripheral blood sampling, facilitating longitudinal monitoring of disease

Effect of neprilysin inhibition on Alzheimer disease plasma biomarkers: a secondary analysis of a randomized clinical trial

WS Brum, KF Docherty, NJ Ashton, H Zetterberg… - JAMA …, 2024 - jamanetwork.com
… Petrie, MD, PhD, from the University of Glasgow for participating as investigators in the
trial and Shorena Janelidze, PhD, from Lund University for participating in plasma biomarker

Predicting progression from mild cognitive impairment to Alzheimer's dementia using clinical, MRI, and plasma biomarkers via probabilistic pattern classification

…, Alzheimer's Disease Neuroimaging Initiative - PloS one, 2016 - journals.plos.org
… blood plasma samples are arguably less invasive and more routinely obtained than CSF
samples, we examined plasma proteomic biomarkers as an alternative to CSF biomarkers. …

Detection of β-amyloid positivity in Alzheimer's Disease Neuroimaging Initiative participants with demographics, cognition, MRI and plasma biomarkers

D Tosun, D Veitch, P Aisen, CR Jack Jr… - Brain …, 2021 - academic.oup.com
… , early/late MCI and dementia), but excluding the participants of this study with plasma
biomarker data. The method yields a probabilistic score of Aβ-positivity between 0 and 1. …

[HTML][HTML] … and proteins in plasma and cerebrospinal fluid as biomarkers for the prediction, diagnosis, and monitoring of therapeutic efficacy of Alzheimer's disease

CD Aluise, RA Sowell, DA Butterfield - … (BBA)-Molecular Basis of Disease, 2008 - Elsevier
… ) have evolved as prime targets for biomarker investigation. This review … plasma and CSF
as candidate biomarkers for AD, and briefly discusses advances in potential urinary biomarkers

Amyloid-β misfolding as a plasma biomarker indicates risk for future clinical Alzheimer's disease in individuals with subjective cognitive decline

J Stockmann, IMW Verberk, N Timmesfeld… - Alzheimer's Research & …, 2020 - Springer
… of different plasma biomarkers would increase the prognostic accuracy. For this purpose,
we considered not only the misfolding of Aβ but also the plasma Aβ 42/40 ratio level. …

Identification of cathepsin D as a plasma biomarker for Alzheimer's disease

JW Kim, SY Jung, Y Kim, H Heo, CH Hong, SW Seo… - Cells, 2021 - mdpi.com
… used as a plasma biomarker for AD. In this study, we aimed to determine whether plasma
cathepsin D could be a useful biomarker for AD diagnosis. We found that plasma cathepsin D …