P-tau217 in Alzheimer's disease
…, L Risch, CH Saely, K Grossmann, P Werner - Clinica Chimica Acta, 2022 - Elsevier
… Further, plasma p-tau217 might have the potential to predict … brain abnormalities associated
with Alzheimer's disease. … , showing that plasma p-tau181 levels are not as high as plasma p-…
with Alzheimer's disease. … , showing that plasma p-tau181 levels are not as high as plasma p-…
Associations of fully automated CSF and novel plasma biomarkers with Alzheimer disease neuropathology at autopsy
…, Alzheimer's Disease Neuroimaging Initiative - Neurology, 2021 - AAN Enterprises
… In a subset of 26 participants, we also analyzed antemortem levels of plasma p-tau181
and neurofilament light (NfL). Reference biomarker values were obtained from 146 amyloid-PET–…
and neurofilament light (NfL). Reference biomarker values were obtained from 146 amyloid-PET–…
Associations of longitudinal plasma p-tau181 and NfL with tau-PET, Aβ-PET and cognition
BS Rauchmann, T Schneider-Axmann… - Journal of Neurology …, 2021 - jnnp.bmj.com
… . Development and assessment of a composite score for memory in the Alzheimer's
disease neuroimaging Initiative (ADNI). Brain Imaging Behav 2012;6:502–16.doi:10.1007/s11682-…
disease neuroimaging Initiative (ADNI). Brain Imaging Behav 2012;6:502–16.doi:10.1007/s11682-…
Plasma biomarkers for prediction of Alzheimer's disease neuropathologic change
… Our findings support that plasma GFAP and p-tau181 may contain the most independent
and complementary information among the four marker measures as both were chosen across …
and complementary information among the four marker measures as both were chosen across …
Blood plasma phosphorylated-tau isoforms track CNS change in Alzheimer's disease
NR Barthélemy, K Horie, C Sato… - Journal of Experimental …, 2020 - rupress.org
… We found p-tau-217 and p-tau-181 were highly specific for amyloid plaque pathology in the
discovery cohort (n = 36, AUROC = 0.99 and 0.98 respectively). In the validation cohort (n = …
discovery cohort (n = 36, AUROC = 0.99 and 0.98 respectively). In the validation cohort (n = …
Plasma p‐tau181/Aβ1‐42 ratio predicts Aβ‐PET status and correlates with CSF‐p‐tau181/Aβ1‐42 and future cognitive decline
…, N Dewit, K Mauroo, P Maruff… - Alzheimer's & …, 2022 - Wiley Online Library
… Plasma p‐tau181/Aβ 1‐42 ratio correlated with cerebrospinal fluid (CSF) p‐tau181 (Elecsys,
Spearman's ρ = 0.74, P … The p‐tau181/Aβ 1‐42 ratio also predicted future rates of cognitive …
Spearman's ρ = 0.74, P … The p‐tau181/Aβ 1‐42 ratio also predicted future rates of cognitive …
Performance of plasma phosphorylated tau 181 and 217 in the community
…, DS Knopman, VJ Lowe, G Bu, P Vemuri… - Nature medicine, 2022 - nature.com
… -tau217 are indicators of both amyloid and tau pathology across the clinical Alzheimer’s
disease (AD) spectrum and can differentiate AD dementia from other neurodegenerative …
disease (AD) spectrum and can differentiate AD dementia from other neurodegenerative …
Characterization of Alzheimer's tau biomarker discordance using plasma, CSF, and PET
…, Alzheimer's Disease Neuroimaging Initiative - Alzheimer's research & …, 2021 - Springer
… p-tau181 may become abnormal earlier than tau-PET, which was demonstrated previously
among Alzheimer’s Disease … discrepancies between plasma p-tau181 and CSF p-tau181 or …
among Alzheimer’s Disease … discrepancies between plasma p-tau181 and CSF p-tau181 or …
Tau proteins in blood as biomarkers of Alzheimer's disease and other proteinopathies
F Verde - Journal of Neural Transmission, 2022 - Springer
… that measurement of plasma phosphorylated tau species (P-tau181, P-tau217, and P-tau231) …
A recent study showed that, while both plasma P-tau181 and plasma NFL distinguished …
A recent study showed that, while both plasma P-tau181 and plasma NFL distinguished …
Phospho‐tau217 and phospho‐tau181 in plasma and CSF as biomarkers for Alzheimer's disease: Clinical study results of AD blood biomarkers
S Janelidze, S Palmqvist, YT Quiroz… - Alzheimer's & …, 2020 - Wiley Online Library
… We compared CSF p-tau217 to CSF p-tau181 in the Swedish BioFINDER-1 cohort (n=194).
We next evaluated plasma p-tau217 and plasma p-tau181 in three cohorts with 1,438 …
We next evaluated plasma p-tau217 and plasma p-tau181 in three cohorts with 1,438 …