The serotonergic system in ageing and Alzheimer's disease
JJ Rodríguez, HN Noristani, A Verkhratsky - Progress in neurobiology, 2012 - Elsevier
… in AD and that several drugs enhancing 5-HT neurotransmission are … of the role of serotonergic
neurotransmission in brain … serotonergic transmission in neurological diseases and AD. …
neurotransmission in brain … serotonergic transmission in neurological diseases and AD. …
Serotonergic drugs: agonists/antagonists at specific serotonergic subreceptors for the treatment of cognitive, depressant and psychotic symptoms in Alzheimer's …
FM Werner, R Covenas - Current pharmaceutical design, 2016 - ingentaconnect.com
… and psychotic symptoms in Alzheimer’s disease. Starting from … serotonergic subreceptors
in the involved brain regions. Results: In the hippocampus and prefrontal cortex, serotonin …
in the involved brain regions. Results: In the hippocampus and prefrontal cortex, serotonin …
Serotonergic system, cognition, and BPSD in Alzheimer's disease
… in almost 90% of patients with Alzheimer's Disease (AD), cause extensive impairment …
systems are capable of inducing psychosis, these are “dirty drugs” that activate a number of …
systems are capable of inducing psychosis, these are “dirty drugs” that activate a number of …
Serotonin: a new hope in Alzheimer's disease?
S Claeysen, J Bockaert, P Giannoni - ACS chemical neuroscience, 2015 - ACS Publications
… drugs target GPCRs and some already target serotonin receptors. Several of these serotonergic
… A critical overview of therapeutic strategy and advancement for Alzheimer's disease …
… A critical overview of therapeutic strategy and advancement for Alzheimer's disease …
Serotonergic therapies for cognitive symptoms in Alzheimer's disease: rationale and current status
… Some of the serotonergic drugs described in this review seem to be promising therapies …
some disease-modifying actions. However, when analysing the effectiveness of a new drug, …
some disease-modifying actions. However, when analysing the effectiveness of a new drug, …
[HTML][HTML] Opportunities for multiscale computational modelling of serotonergic drug effects in Alzheimer's disease
… drugs, targeting alternative neurotransmitter pathways, particularly those targeting serotonergic
(… In this review, we focused on 5-HT receptor (5-HTR) mediated signalling and drugs that …
(… In this review, we focused on 5-HT receptor (5-HTR) mediated signalling and drugs that …
Presynaptic serotonergic dysfunction in patients with Alzheimer's disease
AM Palmer, PT Francis, JS Benton… - Journal of …, 1987 - Wiley Online Library
… serotonergic denervation. Values for serotonergic markers in Alzheimer’s disease sam- …
of serotonergic drugs on glutamatergic neurones may provide a novel therapeutic approach …
of serotonergic drugs on glutamatergic neurones may provide a novel therapeutic approach …
Serotonin and Alzheimer's disease
BA Lawlor - Psychiatric Annals, 1990 - journals.healio.com
… agents in Alzheimer's patients since the … serotonin (T)-HT) lesion in AD. and discusses
how this deficit may contribute to the cognitive and noncognitive symptoms of Alzheimer's …
how this deficit may contribute to the cognitive and noncognitive symptoms of Alzheimer's …
The serotonin 5-HT6 receptor: a viable drug target for treating cognitive deficits in Alzheimer's disease
WJ Geldenhuys, CJ Van der Schyf - Expert review of …, 2009 - Taylor & Francis
… serotonin 6 receptor is attracting attention as an etiological contributor in cognition deficits in
diseases such as Alzheimer’s disease… memory, particularly in Alzheimer’s disease. A surge …
diseases such as Alzheimer’s disease… memory, particularly in Alzheimer’s disease. A surge …
[HTML][HTML] Cholinergic and serotonergic modulation of resting state functional brain connectivity in Alzheimer's disease
BL Klaassens, JMA van Gerven, ES Klaassen… - Neuroimage, 2019 - Elsevier
… stimulation in non-AD subjects mainly shows effects on DMN connectivity, and DMN
coherence is most often found to be altered in AD, we examined drug effects on DMN connectivity …
coherence is most often found to be altered in AD, we examined drug effects on DMN connectivity …
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