Shared mechanisms of neurodegeneration in Alzheimer's disease and Parkinson's disease

A Xie, J Gao, L Xu, D Meng - BioMed research international, 2014 - Wiley Online Library
… This review aims to elucidate the common shared mechanisms in AD and PD (Figure 1)
from gene mechanisms to histological level. Next, we will share these mechanisms. …

Alzheimer's disease and hippocampal adult neurogenesis; exploring shared mechanisms

C Hollands, N Bartolotti, O Lazarov - Frontiers in neuroscience, 2016 - frontiersin.org
Alzheimer's disease mouse models. We review current work suggesting that neuronal
differentiation is defective in Alzheimer's disease, … neurogenesis in Alzheimer's disease. Lastly, we …

Shared cognitive and behavioral impairments in epilepsy and Alzheimer's disease and potential underlying mechanisms

J Chin, HE Scharfman - Epilepsy & Behavior, 2013 - Elsevier
… One potential shared mechanism of cognitive dysfunction in AD and TLE is the seizures …
Moreover, could there be additional shared mechanisms that are not a direct consequence of …

[HTML][HTML] Shared mechanisms: osteoporosis and Alzheimer's disease?

CM Dengler-Crish, F Elefteriou - Aging (Albany NY), 2019 - ncbi.nlm.nih.gov
… for mechanisms of bone loss in AD—work that may provide warning signs for incipient
disease, address quality of life issues in patients with dementia, and identify new mechanisms for …

Shared molecular mechanisms among Alzheimer's disease, neurovascular unit dysfunction and vascular risk factors: a narrative review

L Falsetti, G Viticchi, V Zaccone, E Guerrieri… - Biomedicines, 2022 - mdpi.com
… the literature describing commonly shared molecular pathways … and neurodegenerative
pathology and share several molecular … mechanisms, including NVUd/BBBb. Moreover, vascular …

Neuronal glial crosstalk: specific and shared mechanisms in Alzheimer's disease

V Chavda, K Singh, V Patel, M Mishra, AK Mishra - Brain Sciences, 2022 - mdpi.com
… neuron–glia interactions, which might be a new therapeutic platform to control these deadly
diseases [2,3]. Alzheimer’s poses a major health challenge when we think of mental illness. …

Type 2 diabetes mellitus and Alzheimer's disease: shared molecular mechanisms and potential common therapeutic targets

R Hamzé, E Delangre, S Tolu, M Moreau… - International journal of …, 2022 - mdpi.com
… between type 2 diabetes and Alzheimer’s disease, but to date, … molecular mechanisms that
may link these two diseases, … and DYRK1A, markers of Alzheimer’s disease, which are also …

[HTML][HTML] Inflammation as a central mechanism in Alzheimer's disease

JW Kinney, SM Bemiller, AS Murtishaw… - Alzheimer's & Dementia …, 2018 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative … of microglia-related signaling
mechanisms that have been … and how they may be related to inflammatory mechanisms. …

Mechanisms of neurodegeneration shared between multiple sclerosis and Alzheimer's disease

H Lassmann - Journal of neural transmission, 2011 - Springer
… Multiple sclerosis and Alzheimer’s disease are fundamentally different diseases. However,
… that certain mechanisms of neurodegeneration may be shared between the two diseases. …

Shared pathological pathways of Alzheimer's disease with specific comorbidities: current perspectives and interventions

CM Nday, D Eleftheriadou… - Journal of …, 2018 - Wiley Online Library
… Representative shared mechanisms of Alzheimer's disease with certain comorbidities.
Alterations of the main components of diabetes mellitus, obesity and dyslipidemia can result in …