… continues to remain the best approach in providing symptomatic improvement in patients.
As of late, mechanistic insights into the disease modifying aspects have also been highlighted. …

… , and the observed reduction in Alzheimer's disease suggested a selective destruction of …
AChE inhibitors for Alzheimer's disease therapy. Alternative approaches aiming for improved …

… The “amyloid hypothesis” of Alzheimer's disease is given particular attention, since the
majority of the ongoing therapeutic approaches are based on its theoretical framework. …

… therapeutic approach to AD, we can identify three important fronts: the approved drugs
currently available for the treatment of the disease… and donepezil; therapies under investigation …

… Finally, Aβ clearance through immunotherapy is one of the latest therapeutic approaches …
focused on the therapeutic approach to tau pathology [110]. The proposed therapies aim to …

… In this paper, we reviewed novel therapeutic approaches in five categories: anti-amyloid
therapy, anti-tau therapy, anti-neuroinflammatory therapy, neuroprotective agents including N-…

Despite the fact that Alzheimer’s disease (AD) is the most common cause of dementia, after
many years of research regarding this disease, there is no casual treatment. Regardless of …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder with a deadly …
description of this disease by Alois Alzheimer about 90years ago. Most approaches to explain the …

… development of multiple therapeutic approaches for AD and are the subject of this review. …
Tau-based therapeutic approaches to AD focus on methods to compensate for a loss of tau …

… It is the intent of this chapter to examine the status of the active AD therapeutic approaches
as well as some areas which are only beginning to see medicinal chemistry activity. Our effort …