Alzheimer's disease pathogenesis and therapeutic interventions

MS Parihar, T Hemnani - Journal of clinical neuroscience, 2004 - Elsevier
Alzheimer’s disease (AD) is a neurodegenerative disorder of the central nervous system
associated with progressive cognitive and memory loss. Molecular hallmarks of the disease are …

Current progress, challenges and future prospects of diagnostic and therapeutic interventions in Alzheimer's disease

K Rajasekhar, T Govindaraju - RSC advances, 2018 - pubs.rsc.org
… tools and techniques for diagnostic and therapeutic interventions in AD, especially those in
… molecular tools for diagnostic and therapeutic interventions that target multifaceted toxicity in …

Therapeutic interventions in Alzheimer disease

A Mitra, B Dey - Neurodegenerative diseases, 2013 - books.google.com
… Inflammatory processes and cytokines play a controversial role in the pathology of Alzheimer's
disease. Inflammation is a general marker of tissue damage in any disease, and may be …

Therapeutic approaches to Alzheimer's disease

HW Klafki, M Staufenbiel, J Kornhuber, J Wiltfang - Brain, 2006 - academic.oup.com
… Amyloid cascade hypothesis and selected strategies for therapeutic intervention. The
figure summarizes the presumed sequence of pathological processes that leads to …

Inhibition of γ-secretase as a therapeutic intervention for Alzheimer's disease: prospects, limitations and strategies

G Evin, MF Sernee, CL Masters - CNS drugs, 2006 - Springer
… as a novel approach to Alzheimer’s disease therapy. … are the culprit in Alzheimer’s disease
pathogenesis. Therefore, … constitutes a rational approach for a therapeutic intervention. …

[HTML][HTML] Impact of new drugs for therapeutic intervention in Alzheimer's disease

J Olloquequi, M Ettcheto, A Cano… - Frontiers in Bioscience …, 2022 - imrpress.com
The increases in population ageing and growth are leading to a boosting in the number of
people living with dementia, Alzheimer’s disease (AD) being the most common cause. In spite …

Alzheimer's disease: pathogenesis and therapeutic interventions

JO Ogbodo, CP Agbo, UO Njoku… - Current aging …, 2022 - ingentaconnect.com
… down the progression of Alzheimer's disease. Numerous dietary … Alzheimer's disease.
Furthermore, some researches have revealed that changes in diet can reduce the risk of disease

Mitochondrial therapeutic interventions in Alzheimer's disease

V Van Giau, SSA An, JP Hulme - Journal of the neurological sciences, 2018 - Elsevier
Alzheimer's Disease (AD) is one of the most common age-related neurodegenerative
diseases in the developed world. Treatment of AD is particularly challenging as the drug must …

The role of PGC1α in Alzheimer's disease and therapeutic interventions

BC Mota, M Sastre - International Journal of Molecular Sciences, 2021 - mdpi.com
… In the brains of Alzheimer’s disease (AD) patients and … PGC1α activation as a new therapeutic
avenue for AD, which … expression of PGC1α and gene therapy studies in animal models of …

Multifactorial causal model of brain (dis) organization and therapeutic intervention: Application to Alzheimer's disease

…, Alzheimer's Disease Neuroimaging Initiative - Neuroimage, 2017 - Elsevier
… )organization and therapeutic intervention that accounts for … and identification of optimum
therapeutic interventions. In this … level for studying late onset Alzheimer’s disease (LOAD). By …