Shift in brain metabolism in late onset Alzheimer's disease: implications for biomarkers and therapeutic interventions
… that a successful therapeutic intervention for AD will require very early identification of
prodromal AD patients. Therefore, an area of concentrated focus within the Alzheimer’s research …
prodromal AD patients. Therefore, an area of concentrated focus within the Alzheimer’s research …
Disease-modifying therapies for Alzheimer disease: challenges to early intervention
JL Cummings, R Doody, C Clark - Neurology, 2007 - AAN Enterprises
Prevention of Alzheimer disease (AD) is a national and global imperative. Therapy is
optimally initiated when individuals are asymptomatic or exhibit mild cognitive impairment (MCI). …
optimally initiated when individuals are asymptomatic or exhibit mild cognitive impairment (MCI). …
Current and future therapy in Alzheimer's disease
RJ Van Marum - Fundamental & clinical pharmacology, 2008 - Wiley Online Library
… of rational therapeutic interventions analogous to levodopa treatment of Parkinson’s disease.
… or the cognitive portion of the Alzheimer Disease Assessment Scale. However, positive …
… or the cognitive portion of the Alzheimer Disease Assessment Scale. However, positive …
Therapeutic strategies for Alzheimer's disease
MS Wolfe - Nature Reviews Drug Discovery, 2002 - nature.com
… During the past 10–15 years, the molecular details for the pathogenesis of AD have
become clear enough to outline strategies for therapeutic intervention. Because evidence from …
become clear enough to outline strategies for therapeutic intervention. Because evidence from …
Alzheimer's disease
CL Masters, R Bateman, K Blennow… - Nature reviews disease …, 2015 - nature.com
… To achieve this goal, therapeutic intervention might need to be started by middle-age. Very
long-term treatment with monoclonal antibodies is unlikely to be practical; however, an active …
long-term treatment with monoclonal antibodies is unlikely to be practical; however, an active …
[HTML][HTML] Gut-brain axis and Alzheimer's disease: Therapeutic interventions and strategies
H Singh, C Chopra, H Singh, V Malgotra… - Journal of Functional …, 2024 - Elsevier
… However, the therapy of memory loss with probiotics, notably in individuals with
Alzheimer's disease, and its therapeutic effects are not well studied. This review highlights the …
Alzheimer's disease, and its therapeutic effects are not well studied. This review highlights the …
The mitochondrial dynamics of Alzheimer's disease and Parkinson's disease offer important opportunities for therapeutic intervention
Mitochondrial dynamics play a crucial role in the pathobiology underlying Alzheimer's disease
(AD) and Parkinson's disease (PD). Although a complete scientific understanding of these …
(AD) and Parkinson's disease (PD). Although a complete scientific understanding of these …
[HTML][HTML] Mitochondrial dysfunction and Alzheimer's disease: prospects for therapeutic intervention
Alzheimer’s disease (AD) is a multifactorial neurodegenerative disease and has become a
major socioeconomic issue in many developed countries. Currently available therapeutic …
major socioeconomic issue in many developed countries. Currently available therapeutic …
Meditation as a therapeutic intervention for adults at risk for Alzheimer's disease–potential benefits and underlying mechanisms
Alzheimer’s disease (AD) is a chronic, progressive, brain disorder that affects at least 5.3
million Americans at an estimated cost of $148 billion, figures that are expected to rise steeply …
million Americans at an estimated cost of $148 billion, figures that are expected to rise steeply …
Disease-modifying therapies in Alzheimer's disease
S Salloway, J Mintzer, MF Weiner, JL Cummings - Alzheimer's & dementia, 2008 - Elsevier
… posited pathways of AD pathogenesis and the opportunities for therapeutic interventions. …
In research conducted by the Alzheimer Disease Cooperative Study, the effects of vitamin E, …
In research conducted by the Alzheimer Disease Cooperative Study, the effects of vitamin E, …