… that a successful therapeutic intervention for AD will require very early identification of
prodromal AD patients. Therefore, an area of concentrated focus within the Alzheimer’s research …

Prevention of Alzheimer disease (AD) is a national and global imperative. Therapy is
optimally initiated when individuals are asymptomatic or exhibit mild cognitive impairment (MCI). …

… of rational therapeutic interventions analogous to levodopa treatment of Parkinson’s disease.
… or the cognitive portion of the Alzheimer Disease Assessment Scale. However, positive …

… During the past 10–15 years, the molecular details for the pathogenesis of AD have
become clear enough to outline strategies for therapeutic intervention. Because evidence from …

… To achieve this goal, therapeutic intervention might need to be started by middle-age. Very
long-term treatment with monoclonal antibodies is unlikely to be practical; however, an active …

… However, the therapy of memory loss with probiotics, notably in individuals with
Alzheimer's disease, and its therapeutic effects are not well studied. This review highlights the …

Mitochondrial dynamics play a crucial role in the pathobiology underlying Alzheimer's disease
(AD) and Parkinson's disease (PD). Although a complete scientific understanding of these …

Alzheimer’s disease (AD) is a multifactorial neurodegenerative disease and has become a
major socioeconomic issue in many developed countries. Currently available therapeutic …

Alzheimer’s disease (AD) is a chronic, progressive, brain disorder that affects at least 5.3
million Americans at an estimated cost of $148 billion, figures that are expected to rise steeply …

… posited pathways of AD pathogenesis and the opportunities for therapeutic interventions. …
In research conducted by the Alzheimer Disease Cooperative Study, the effects of vitamin E, …