… prevalent disease. Here, we will summarize and discuss the evidence for vascular alterations,
… in the elderly population, comparing them with vascular alterations in AD brain. The most …

… Alzheimer's Disease Neuroimaging Initiative (ADNI) and modelling of late-onset AD (LOAD)
suggest that vascular … and physiological alterations to the cerebral vasculature affect vessel …

… affect the cerebral vasculature. Conversely, alterations of the cerebral vessels might have
systemic effects. We know that many brain diseases are associated with vascular dysfunctions. …

… Morphologically, pericytes can be seen to undergo alterations in the AD brain, with
cytosolic … This study also noted significant subcellular mitochondrial alterations in pericytes, …

… on the roles of cerebrovascular diseases and systemic vascular diseases in AD need to be
… the cerebral vasculature, cardiac vasculature, and apoE that lead us to contend that vascular …

… origin of the disease development. At neuroimaging, signs of vascular dysfunction such as
… even before cognitive decline and alteration of traditional biomarkers. Cerebral small vessel …

… two-hit vascular hypothesis and vascular alterations occurring in the disease. According to
… starts as a consequence of damage in the cerebral vasculature. Given that there are several …

… Section Vasculature in Alzheimer's Disease below focuses on … vascular changes
discussed for the main mice models in this section (Section Vasculature in Alzheimer's Disease…

… Ultimately, holes are formed in the vascular system, accompanied by vascular remodeling. …
vascular changes, imaging vascular alterations could be used as biomarker for the disease …

… vascular alterations was correlated with the presence of neurofibrillary tangles. However,
vascular … , we and others have demonstrated vascular alterations in aging and AD. In aging, …