Alzheimer disease pathology and the cerebrospinal fluid proteome
… MS-based proteomic biomarker discovery workflow, we measured cerebrospinal fluid (CSF)
proteomes to explore their association with well-established markers of core AD pathology. …
proteomes to explore their association with well-established markers of core AD pathology. …
Cerebrospinal fluid proteomics and biological heterogeneity in Alzheimer's disease: a literature review
KEJ Wesenhagen, CE Teunissen… - Critical reviews in …, 2020 - Taylor & Francis
… to study AD disease mechanisms. Here, we review the CSF proteomics literature to identify
… on these proteins to study which biological processes may be involved in the disease. …
… on these proteins to study which biological processes may be involved in the disease. …
Pathophysiological subtypes of Alzheimer's disease based on cerebrospinal fluid proteomics
…, Alzheimer's Disease Neuroimaging Initiative (ADNI)… - Brain, 2020 - academic.oup.com
… ) of Alzheimer's disease polygenic risk scores for increasing SNP inclusion P-value thresholds,
comparing Alzheimer's disease … of Alzheimer's disease subtypes in Alzheimer's disease …
comparing Alzheimer's disease … of Alzheimer's disease subtypes in Alzheimer's disease …
Proteome profiling in cerebrospinal fluid reveals novel biomarkers of Alzheimer's disease
… A robust proteomic workflow quantifies more than 1,000 proteins in cerebrospinal fluid and
reveals an Alzheimer's Disease-associated signature of more than 20 proteins across three …
reveals an Alzheimer's Disease-associated signature of more than 20 proteins across three …
Plasma proteomic profiles of cerebrospinal fluid-defined Alzheimer's disease pathology in older adults
… In the present study, plasma proteome profiles of 120 elderly … our proteomic results suggest
that several panels of plasma proteins are relevant to CSF-defined AD and amyloid pathology…
that several panels of plasma proteins are relevant to CSF-defined AD and amyloid pathology…
Cerebrospinal fluid proteomic biomarkers for Alzheimer's disease
EJ Finehout, Z Franck, LH Choe… - Annals of Neurology …, 2007 - Wiley Online Library
… Here, we compare the proteomes of 34 antemortem CSF samples from AD patients with that
… We characterize the CSF proteomes using 2DE and analyze the resulting quantitative data …
… We characterize the CSF proteomes using 2DE and analyze the resulting quantitative data …
Cerebrospinal fluid proteomics in patients with Alzheimer's disease reveals five molecular subtypes with distinct genetic risk profiles
BM Tijms, EM Vromen, O Mjaavatten, H Holstege… - Nature aging, 2024 - nature.com
… Here we define AD molecular subtypes using mass spectrometry proteomics in cerebrospinal
fluid, based on 1,058 proteins, with different levels in individuals with AD (n = 419) …
fluid, based on 1,058 proteins, with different levels in individuals with AD (n = 419) …
Quantitative proteomic profiling of cerebrospinal fluid to identify candidate biomarkers for Alzheimer's disease
… The aim of this study is to identify the potential cerebrospinal fluid (CSF) biomarkers for
Alzheimer's disease and to evaluate these markers on independent CSF samples using parallel …
Alzheimer's disease and to evaluate these markers on independent CSF samples using parallel …
Proteome analysis of cerebrospinal fluid proteins in Alzheimer patients
P Davidsson, A Westman-Brinkmalm, CL Nilsson… - …, 2002 - journals.lww.com
… By comparing the CSF proteome between Alzheimer disease (AD) patients and controls it
may be possible to identify proteins that play a role in the disease process and thus to study …
may be possible to identify proteins that play a role in the disease process and thus to study …
Analysis of the cerebrospinal fluid proteome in Alzheimer's disease
… for monitor of disease progression. In … cerebrospinal fluid proteome of Alzheimer’s disease
patients and non-demented controls to identify potential biomarkers for Alzheimer’s disease. …
patients and non-demented controls to identify potential biomarkers for Alzheimer’s disease. …