… We began by evaluating behavioral impairment in three cohorts of WT and TgF344-AD
rats at 6, 15, and 24 months of age. Neurologic screening did not reveal between-genotype …

… The McGill-R-Thy1-APP transgenic rat is an animal model of the familial form of Alzheimer's
… homozygous McGill rats exhibit a complex phenotype and behavioral impairments beyond …

… effects associated with neurodegenerative diseases, including Alzheimer’s Disease (AD). …
AD cognitive and behavioral impairments using a sporadic AD-like rat model, established …

… It is of significance that the McGill-R-Thy1-APP rat presents progressive behavior impairments
in the MWM starting at 3 months of age while no amyloid plaques are yet present. The …

… When compared to wild-type (WT), male Tg +/− rats exhibited … Tg +/− rats displayed a working
memory impairment in the Y-… rat has a wide array of behavioral and cognitive impairments …

… plasticity and behavioral impairment in this study is by the alteration to cholinergic
neurotransmitter system, as evidenced by upregulation of AChE in glutamate infused rats. The main …

… The deficit in LTP was accompanied by impaired spatial learning and memory in the Morris
… rats of 13 months of age. For Tg rats of both ages, there was a trend for cognitive impairment …

… forced exercise trainings on behavioral impairment as well as hippocampal Alzheimer’s
disease … in the rat model of AD. The rats were assigned to control, Alzheimer model, Alzheimer + …

… physiological, behavioral, biochemical and morphological impacts 6 weeks after injection in
rats. … for the delayed learning and memory impairments observed in oAβ 25–35 treated rats. …

… f3-amyloid protein-treated rats could be used as an animal model for AD. /3-amyloid protein;
Alzheimer's disease; memory; choline acetyltransferase; rats Alzheimer's disease (AD) is …