The prevalence of apparent amiodarone-related hepatic injury in 104 patients followed
prospectively is compared to that reported in the literature. Asymptomatic elevation of serum …

… It appears that the duration of treatment and the dosage of amiodarone are not directly
correlated with the degree of injury. Lamellated lysosomal inclusion bodies were found in all …

… This analysis of the morphology of suspected amiodarone (AD) liver disease is based on a
… These changes of pseudoalcoholic hepatitis and/or phospholipidosis were present in liver …

… The use of amiodarone was considered to be reasonable and … amiodarone can cause
hepatotoxicity and hepatic function tests should be performed soon after giving amiodarone …

… amiodarone-induced irreversible hepatotoxicity showed liver cirrhosis during treatment with
amiodarone and died of hepatic failure; the other patient, who had reversible hepatotoxicity, …

… -amiodarone ALT and AST were significantly correlated with … -amiodarone AST, but not ALT,
was significantly correlated … a risk factor for IV amiodarone induced hepatotoxicity which was …

… , or chronic active hepatitis. Less well recognized is the fact that amiodarone has been
attributed to six deaths. We cared for a patient with amiodarone hepatotoxicity, which led us to …

… the prevalence of amiodarone hepatotoxicity in a cohort receiving chronic amiodarone
therapy, … Prospective studies showed that amiodarone hepatic toxicity correlates to steady state …

… With prolonged treatment, amiodarone hepatotoxicity may insidiously progress to cirrhosis
and present with signs and symptoms of decompensated liver failure, portal hypertension, …

… In some patients developing liver disease while being treated with amiodarone, a morphologic
picture resembling alcoholic hepatitis has been described. This kind of severe drug-…