Causality assessment of liver injury after chronic oral amiodarone intake

L Llanos, R Moreu, AM Peiró, S Pascual… - … and Drug Safety, 2009 - Wiley Online Library
amiodarone will increase in future years. As clinically significant hepatotoxicity associated
with oral amiodarone … to help in the causality assessment of amiodarone-induced liver injury. …

Incidence rate of adverse drug reactions during long-term follow-up of patients newly treated with amiodarone

V Bongard, D Marc, V Philippe… - American journal of …, 2006 - journals.lww.com
amiodarone. Table 1 summarizes kind and number of ADRs recorded during the follow-up
and the causality assessment of amiodarone … elucidate whether iodine intake may effectively …

Critical evaluation of causality assessment of herb–drug interactions in patients

C Awortwe, M Makiwane, H Reuter… - British journal of …, 2018 - Wiley Online Library
… The data were extracted and the causal relationship of ADRs as consequences of HDI
assessed using Horn's drug interaction probability scale or Roussel Uclaf Causality Assessment

Examining the safety of amiodarone

P Santangeli, L Di Biase, JD Burkhardt… - Expert opinion on …, 2012 - Taylor & Francis
… focused on amiodarone safety, once directly comparing amiodarone with placebo, then
the NNT and NNH are the number of patients we would need to treat with the amiodarone to …

Adverse effects of low dose amiodarone: a meta-analysis

VR Vorperian, TC Havighurst, S Miller… - Journal of the American …, 1997 - jacc.org
… We sought to assess the odds of experiencing adverse effects with low dose amiodarone
Nonetheless, an objective assessment of the likelihood of experiencing amiodarone-related …

[HTML][HTML] A rare case of intravenous amiodarone toxicity

AL Dos Santos, M Lagarto, C Gouveia - Cureus, 2022 - ncbi.nlm.nih.gov
… There was no history of alcohol intake or illicit drug use. No medication adherence. No …
score, that helps to assess the likelihood of drug-induced liver injury. Causality assessment by the …

Amiodarone hepatotoxicity

M Babatin, SS Lee, PT Pollak - Current vascular pharmacology, 2008 - ingentaconnect.com
… Because confounding variables such as alcohol intake, obesity and … causality in a case
of suspected drug-induced hepatotoxicity is often difficult. It is certainly logical that amiodarone

Effects of amiodarone therapy on thyroid function

J Cohen-Lehman, P Dahl, S Danzi, I Klein - Nature reviews …, 2010 - nature.com
… The absorption of amiodarone is slow and variable, ranging from 22–80%, the latter effect …
at the time of drug intake. The drug's bioavailability is approximately 40%. Amiodarone is very …

Causality assessment in drug-induced hepatotoxicity

RJ Andrade, R Camargo, MI Lucena… - Expert Opinion on …, 2004 - Taylor & Francis
… The latter has allowed causality assessments to be made with more confidence and has
stimulated … In fact, undetected drug intake should be suspected from the presence of any of the …

Association between N-desethylamiodarone/amiodarone ratio and amiodarone-induced thyroid dysfunction

M Yamato, K Wada, M Fujimoto, K Hosomi… - European journal of …, 2017 - Springer
intake, whereas AMD-induced hypothyroidism is more common in iodine-sufficient areas [9,
13, 14]. A daily iodine intake … initiation and development of amiodarone-induced pulmonary …