… that entered the market (an overview of available solid dispersions is … solid state properties
of amorphous solid dispersions. Among the different analytical techniques available for solid …

… is typically low in these types of systems. In an amorphous solid dispersion (ASD), the solubility
of the … lattice to produce a higher energy amorphous form. Compared with other enabling …

… molecules through the preparation of an amorphous solid dispersion (ASD) has become a
routine practice for small molecule drugs exhibiting poor aqueous solubility. Since the idea of …

… on amorphous solid dispersions state that dispersions can … of the increased solubility
exhibited by the amorphous drug. … ) offer advantages for low solubility drugs by producing sink …

… delivery area, particularly in the field of amorphous solid dispersion. He is inventor and co-…
to meet the growing challenges of poor aqueous solubility. During her tenure at Roche, she …

… If a supersaturated drug solution exceeds the amorphous solubility, this amorphous phase
will form … The stable state is limited by the API solubility, which is poor by default for BCS (…

… drugs is to develop amorphous solid dispersions. Reduction in drug … poor solubility and
dissolution rate limited bioavailability. As Gibbs free energy is higher, the solubility of amorphous …

… aqueous dispersions of amorphous solid dispersions (ASDs) on molecular/apparent solubility
… Thus, the bioavailability of these drugs is restricted by their poor solubility. In accordance …

… approaches to improve the overall solubility, dissolution rate, and bioavailability of drugs with
poor water solubility. Moreover, the development of amorphous solid dispersion (SD) using …

… stabilize amorphous forms of low solubility drugs [15,16]. Due to the low MW components, low
… units and hygroscopicity problems inherent to polymeric amorphous SDs are avoided [10]. …