Excitotoxic protection by polyanionic polysaccharide: Evidence of a cell survival pathway involving AMPA receptor–MAPK Interactions

LM Chicoine, BA Bahr - Journal of neuroscience research, 2007 - Wiley Online Library
… , as is the case for polysaccharide modulation of AMPA receptor activity (Sinnarajah et al., …
, a polysaccharide that promotes AMPA receptor signaling. The polysaccharide also protected …

Sulfate‐and size‐dependent polysaccharide modulation of AMPA receptor properties

LM Chicoine, V Suppiramaniam… - Journal of …, 2004 - Wiley Online Library
… In the experiments described here, dextran sulfate of 500 kDa was tested for its ability to
modulate AMPA receptor properties. Dextran sulfate is a freely soluble polyanion that mimics …

[图书][B] Polysaccharide modulation of AMPA-type glutamate receptors: Importance to synaptic function and neuronal maintenance

LM Chicoine - 2003 - search.proquest.com
… Therefore, I will focus on polysaccharide-mediated modulation of AMPA receptor activity
in … Dextran sulfate is a freely soluble polyanion that mimics natural mucopolysaccharides …

Heparin modulates the single channel kinetics of reconstituted AMPA receptors from rat brain

S Sinnarajah, V Suppiramaniam, KP Kumar, RA Hall… - Synapse, 1999 - Wiley Online Library
… The heparin effects were specific as another polysaccharide, dextran, and a monomeric …
receptor) by heparin and other polyanions is calcium dependent. Mol Biol Cell 4:347–352. …

Polysaccharides from wolfberry antagonizes glutamate excitotoxicity in rat cortical neurons

YS Ho, MS Yu, SY Yik, KF So, WH Yuen… - Cellular and molecular …, 2009 - Springer
… a polyanion that mimics natural mucopolysacchardies such as heparin sulfate, is able to alter
binding and channel properties of AMPA receptors (… to interfere AMPA receptor has beyond …

[PDF][PDF] Neuroprotective effect of fucoidan against N-methyl-D-aspartate-induced excitotoxicity in rat hippocampus

YJ Ha, YS Kim, HJ Lee, JH Seo… - Experimental …, 2009 - synapse.koreamed.org
… Fucoidan, a sulfated polyanionic polymer of L-fucose, is obtained from brown marine macroalgae.
… Fucoidan is obtained from brown marine macroalgae, and it is a sulfated polyanionic

Extracts of Liriopsis tuber protect AMPA induced brain damage and improve memory with the activation of insulin receptor and ERK I/II

SJ Kim, K Lee - … Research: An International Journal Devoted to …, 2008 - Wiley Online Library
… Recent studies revealed that AMPA receptors might play a key role in the occurrence of …
by polyanionic polysaccharide: evidence of a cell survival pathway involving AMPA receptor-…

Direct binding of polysialic acid to a brain-derived neurotrophic factor depends on the degree of polymerization

Y Kanato, K Kitajima, C Sato - Glycobiology, 2008 - academic.oup.com
… the homopolymer of sialic acid and negatively regulates neuronal cell–cell and cell–extracellular
matrix interactions through steric and repulsive hindrance due to its bulky polyanionic

A highly sulfated chondroitin sulfate preparation, CS‐E, prevents excitatory amino acid‐induced neuronal cell death

Y Sato, K Nakanishi, Y Tokita… - Journal of …, 2008 - Wiley Online Library
… To assess neuroprotective activities of highly sulfated polysaccharides other than CS-E,
we added heparin (10 and 100 μg/mL) and dextran sulfate (10 and 100 μg/mL) separately to …

Heparin/heparan sulfates bind to and modulate neuronal L-type (Cav1. 2) voltage-dependent Ca2+ channels

G Garau, P Magotti, M Heine, S Korotchenko… - Experimental …, 2015 - Elsevier
… 2α1 that might interact with polyanionic saccharides, we used … to detect interactions with
polysaccharides, these peptides … its binding to different polysaccharides, chondroitin sulfate, …