Resveratrol supplement inhibited the NF-κB inflammation pathway through activating AMPKα-SIRT1 pathway in mice with fatty liver

Y Tian, J Ma, W Wang, L Zhang, J Xu, K Wang… - Molecular and cellular …, 2016 - Springer
… that this AMPKα-SIRT1 metabolic sensing pathway played a dominant … inflammation level
in mice with steatohepatitis. In vivo, we found that the AMPKα phosphorylation level and SIRT1

Omega-3 polyunsaturated fatty acids antagonize macrophage inflammation via activation of AMPK/SIRT1 pathway

B Xue, Z Yang, X Wang, H Shi - 2012 - journals.plos.org
SIRT1 interact to regulate macrophage inflammation. Here we aim to determine whether ω-3
PUFAs antagonize macrophage inflammation via activation of AMPK/SIRT1 pathwaySIRT1

Hesperetin, a SIRT1 activator, inhibits hepatic inflammation via AMPK/CREB pathway

S Wang, W Wang, H Sheng, Y Bai, Y Weng… - International …, 2020 - Elsevier
… that SIRT1 is required for the inhibitory effect of hesperetin on inflammation. Hesperetin
suppresses the acetylation of RelA/p65 to reduce NF-κB activity by inducing SIRT1 expression. …

Activation of AMPK restored impaired autophagy and inhibited inflammation reaction by up-regulating SIRT1 in acute pancreatitis

XD Wang, WL Yu, Y Sun - Life Sciences, 2021 - Elsevier
SIRT1 pathway is involved in a variety of diseases, but its role in AP remains elusive. This
study was aimed to explore the role of AMPK-SIRT1 pathway … of p-AMPKα, SIRT1 were …

[HTML][HTML] … treatment with quercetin and resveratrol attenuates high fat diet‑induced obesity and associated inflammation in rats via the AMPKα1/SIRT1 signaling pathway

L Zhao, F Cen, F Tian, MJ Li… - Experimental and …, 2017 - spandidos-publications.com
… and sirtuin 1 (SIRT1) expression in EAT. In conclusion, CQR may suppress obesity and
associated inflammation via the AMPKα1/SIRT1 signaling pathway in rats fed a HFD. …

Macrophage α1 AMP-activated protein kinase (α1AMPK) antagonizes fatty acid-induced inflammation through SIRT1

Z Yang, BB Kahn, H Shi, B Xue - Journal of Biological Chemistry, 2010 - ASBMB
inflammation, which acts through SIRT1, thereby contributing to the protection against
obesity, inflammation… We also examined the inflammatory pathways in free fatty acid (FFA)-treated …

… systematic understanding of geniposide in ameliorating inflammatory responses in colitis through suppression of NLRP3 inflammasome in macrophage by AMPK/Sirt1 …

Z Pu, Y Liu, C Li, M Xu, H Xie, J Zhao - The American Journal of …, 2020 - World Scientific
… regulator of transcription 1 (SIRT1)-dependent pathway (Cheng … SIRT1 is that AMPK
promotes the production of SIRT1AMPKα/Sirt1 signals may participate in the anti-inflammation

Catechin attenuates TNF-α induced inflammatory response via AMPK-SIRT1 pathway in 3T3-L1 adipocytes

AW Cheng, X Tan, JY Sun, CM Gu, C Liu, X Guo - PLoS One, 2019 - journals.plos.org
… -SIRT1-FoxO3a pathway by catechine may exert beneficial effects on inflammation treatment.
… -α stimulated inflammation by suppressing the activation of NF-κB and FOXO3a via AMPK/…

Pharmacological activation of AMPK ameliorates perivascular adipose/endothelial dysfunction in a manner interdependent on AMPK and SIRT1

Y Sun, J Li, N Xiao, M Wang, J Kou, L Qi… - Pharmacological …, 2014 - Elsevier
… 1 (SIRT1) show similarities in modulation of metabolic pathway, we hypothesized that activation
of AMPK and SIRT1 in PVAT … We observed that PA stimulation induced inflammation and …

Geniposide alleviates diabetic nephropathy of mice through AMPK/SIRT1/NF-κB pathway

F Li, Y Chen, Y Li, M Huang, W Zhao - European Journal of Pharmacology, 2020 - Elsevier
… of GE on DN are associated with concomitant hypoglycemic effect, anti-inflammation
responses and inhibition of podocyte pyroptosis by the activation of AMPK/SIRT1/NF-κB pathway. …