AMPK: guardian of metabolism and mitochondrial homeostasis
… in research on the regulation of autophagy and mitochondrial homeostasis by … is activated
by intracellular calcium. Several factors lead to AMPK activation, such as mitochondrial …
by intracellular calcium. Several factors lead to AMPK activation, such as mitochondrial …
AMPK, mitochondrial function, and cardiovascular disease
S Wu, MH Zou - International journal of molecular sciences, 2020 - mdpi.com
… of AMPK structure and regulation, and then focus on the recent advances toward understanding
how mitochondrial dysfunction controls AMPK and how AMPK, … , maintains mitochondrial …
how mitochondrial dysfunction controls AMPK and how AMPK, … , maintains mitochondrial …
[PDF][PDF] AMPK and transcriptional regulation
SL McGee, M Hargreaves - Front Biosci, 2008 - article.imrpress.com
… gene networks regulated by AMPK, examples of a number of AMPK responsive genes are
presented in Table 1. While very few studies have established bona fide AMPK transcriptional …
presented in Table 1. While very few studies have established bona fide AMPK transcriptional …
AMPK regulation of fatty acid metabolism and mitochondrial biogenesis: implications for obesity
… Skeletal muscle AMPK is also thought to be important for regulating fatty acid metabolism; …
of AMPK in regulating skeletal muscle fatty acid metabolism and mitochondrial biogenesis at …
of AMPK in regulating skeletal muscle fatty acid metabolism and mitochondrial biogenesis at …
The role of AMPK in controlling metabolism and mitochondrial biogenesis during exercise
K Marcinko, GR Steinberg - Experimental physiology, 2014 - Wiley Online Library
… Likewise, AMPK is essential for maintaining muscle mitochondrial … through regulation of the
peroxisome proliferator-activated … role of skeletal muscle AMPK in regulating glucose and FA …
peroxisome proliferator-activated … role of skeletal muscle AMPK in regulating glucose and FA …
Role of AMPK-mediated adaptive responses in human cells with mitochondrial dysfunction to oxidative stress
SB Wu, YT Wu, TP Wu, YH Wei - Biochimica et Biophysica Acta (BBA) …, 2014 - Elsevier
… Recently, we demonstrated that AMPK activation plays a crucial role in the regulation of the
intracellular NADPH level in primary cultures of skin fibroblasts from MERRF patients [45]. It …
intracellular NADPH level in primary cultures of skin fibroblasts from MERRF patients [45]. It …
AMPK activation through mitochondrial regulation results in increased substrate oxidation and improved metabolic parameters in models of diabetes
Y Jenkins, TQ Sun, V Markovtsov, M Foretz, W Li… - PloS one, 2013 - journals.plos.org
… mitochondrial function and the role of AMPK activation in these effects remain unclear. We
have identified a molecule, named R419, that activates AMPK … dependent on AMPK activation, …
have identified a molecule, named R419, that activates AMPK … dependent on AMPK activation, …
New insights into activation and function of the AMPK
GR Steinberg, DG Hardie - Nature reviews Molecular cell biology, 2023 - nature.com
… on the regulation of … for AMPK involved in autophagy, ferroptosis, mitochondrial and
lysosomal homeostasis and DNA repair. Finally, we discuss recent findings on the role of AMPK in …
lysosomal homeostasis and DNA repair. Finally, we discuss recent findings on the role of AMPK in …
[HTML][HTML] Antidiabetic effect of salvianolic acid A on diabetic animal models via AMPK activation and mitochondrial regulation
G Qiang, X Yang, L Shi, H Zhang, B Chen… - Cellular Physiology and …, 2015 - karger.com
… We found that SalA also activated phosphorylation of AMPK in HeLa cells, suggesting
that LKB1 might not be the upstream kinase of AMPK (Fig. 7G). Pretreatment with specific …
that LKB1 might not be the upstream kinase of AMPK (Fig. 7G). Pretreatment with specific …
Starvation-induced autophagy is regulated by mitochondrial reactive oxygen species leading to AMPK activation
… Our findings for a role of mitochondrial regulated ROS in autophagy could provide targets
for the development of novel drugs or provide approaches for controlling autophagy in human …
for the development of novel drugs or provide approaches for controlling autophagy in human …
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