Amyloid-β aggregation
VH Finder, R Glockshuber - Neurodegenerative Diseases, 2007 - karger.com
… The plaques predominantly consist of aggregates of amyloid-β (Aβ), a peptide of 39–42 …
of the amyloid precursor protein. There is a growing body of evidence that Aβ aggregates are …
of the amyloid precursor protein. There is a growing body of evidence that Aβ aggregates are …
Membrane-Accelerated Amyloid-β Aggregation and Formation of Cross-β Sheets
A Khondker, RJ Alsop, MC Rheinstädter - Membranes, 2017 - mdpi.com
… , A β aggregation … β aggregates in Alzheimer’s disease; however, we also see that the
presence of a membrane support can mediate the formation of aggregates and molecular cross- β …
presence of a membrane support can mediate the formation of aggregates and molecular cross- β …
Polyphenols with anti-amyloid β aggregation show potential risk of toxicity via pro-oxidant properties
… Amyloid β (Aβ) aggregation has been the focus for a therapeutic target for the treatment of
… Numerous studies have suggested that accumulation of the Amyloid β (Aβ) peptide in the …
… Numerous studies have suggested that accumulation of the Amyloid β (Aβ) peptide in the …
Inhibitory Activity on Amyloid-β Aggregation and Antioxidant Properties of Crocus sativus Stigmas Extract and Its Crocin Constituents
MA Papandreou, CD Kanakis… - Journal of agricultural …, 2006 - ACS Publications
… is characterized pathologically by deposition of amyloid β-peptide (Aβ) fibrils… properties of
extract of C. sativus stigmas and its effect on Aβ 1-40 fibrillogenesis. The antioxidant properties …
extract of C. sativus stigmas and its effect on Aβ 1-40 fibrillogenesis. The antioxidant properties …
Amyloid-beta aggregation: selective inhibition of aggregation in mixtures of amyloid with different chain lengths
SW Snyder, US Ladror, WS Wade, GT Wang… - Biophysical journal, 1994 - cell.com
… Aggregation is strongly accelerated by increasing salt concentration, again revealing the
dependence of aggregation properties on handling conditions. In addition, aggregation is …
dependence of aggregation properties on handling conditions. In addition, aggregation is …
The ratio of monomeric to aggregated forms of Aβ40 and Aβ42 is an important determinant of amyloid-β aggregation, fibrillogenesis, and toxicity
… Aggregation and fibril formation of amyloid-β (Aβ) peptides … different stages of aggregation
along the amyloid formation pathway. … , and morphological properties of Aβ42 aggregates and …
along the amyloid formation pathway. … , and morphological properties of Aβ42 aggregates and …
Methods for analysis of amyloid-β aggregates
KA Bruggink, M Müller, HB Kuiperij… - Journal of Alzheimer's …, 2012 - content.iospress.com
… (for an overview on microscopic techniques to visualize amyloid plaques and fibrillogenesis,
see Harris [23]). Here, we will consider aggregation forms of Aß and their appearance using …
see Harris [23]). Here, we will consider aggregation forms of Aß and their appearance using …
Studies on the role of amino acid stereospecificity in amyloid beta aggregation
… investigated the aggregation property of … properties of Aβ(1-40) all-L and Aβ(1-40) all-D
enantiomers using various biophysical techniques. These results indicated that the aggregation …
enantiomers using various biophysical techniques. These results indicated that the aggregation …
New insights on how metals disrupt amyloid β-aggregation and their effects on amyloid-β cytotoxicity
Y Yoshiike, K Tanemura, O Murayama, T Akagi… - Journal of Biological …, 2001 - ASBMB
… Amyloid-β protein (Aβ) aggregates in the brain to form senile … Cu(II) normally inhibit amyloid
β-aggregation. Another method for … of aggregates, showed that these metals induce a non-β-…
β-aggregation. Another method for … of aggregates, showed that these metals induce a non-β-…
The properties of amyloid-β fibrils are determined by their path of formation
K Brännström, T Islam, AL Gharibyan, I Iakovleva… - Journal of molecular …, 2018 - Elsevier
… We also show that the transfer of fibrillar properties is restricted to fibril-end templating and
… fibrillar properties of Aβ1–42 and exposes that the transfer of properties between amyloid-β …
… fibrillar properties of Aβ1–42 and exposes that the transfer of properties between amyloid-β …
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