… of PiB–PET to detect longitudinal changes in amyloid-β deposition. First, the degree of
regional retention of PiB is highly correlated with the regional concentration of amyloid-β, as …

… amyloid … amyloid burden by using [ 11C]PIB PET. Our hypothesis was that there is an
association between CSF biomarkers and brain amyloid accumulation quantified by [ 11C]PIB PET. …

… imaging was directly related to Aβ-containing amyloid … that amyloid deposition by [ 11 C]PIB
PET allows for an earlier and more specific AD diagnosis [8]. Amyloid PET with [ 11 C]PIB is …

… )-PET as a measure of brain fibrillar Aβ. Differences in the incidence of amyloid-related …
We report additional analyses of the 11 C-PiB-PET data that evaluate the effects of APOE ε4 …

… We assessed Thal amyloid phase (N = 36) and CERAD score (N = 54) versus both global
and regional PiB SUVRs. In experiment 2 (N = 42), PiB SUVR and post-mortem amyloid β …

… )-PET over the follow-up period, and little increase in PiB retention. These data suggest that
the PET result was either false positive, if PiB … , or true positive if PiB retention began long …

… The point that best separated the two distributions into PIB-PET(+) and PIB-PET(−) was
1.6, as determined by the minimum density value of the PIB-PET scores lying between the 2 …

… hallmarks of AD, fibrillar amyloid β (Aβ) plaques, shows great potential to meet these aims. …
on results from the rapidly expanding literature of PIB-PET in AD, dementia with Lewy bodies (…

… B ( 11 C-PiB) PET is a marker of cortical fibrillar amyloid-β load in vivo. We used 11 C-PiB
PET to investigate whether bapineuzumab, a humanised anti-amyloid-β monoclonal antibody, …

… -type CSF biomarker profile (low amyloid β-protein [Aβ] and … 11 C]PIB) is a PET ligand that
binds to amyloid plaques and has … [ 11 C]PIB uptake with a pattern resembling that seen in AD. …