… Amyloid plaques are one of the two hallmarks of Alzheimer’s disease (… self-assembled
amyloid-β (Aβ) peptides. Aβ is produced in healthy brains from proteolytic cleavage of the amyloid …

Aggregation of amyloid-β (Aβ) by self-assembly into oligomers or amyloids is a central event
in Alzheimer’s disease. Coordination of transition-metal ions, mainly copper and zinc, to Aβ …

… of amyloid-β peptide (Aβ) implicated in Alzheimer’s disease (AD). The presence of elevated
levels of metal ions in the amyloid … retardation of amyloid β peptide fibril formation. Proc. Natl. …

… The self-assembly of peptides and proteins into amyloid fibrils and other aggregates are …
One of the most studied cases is the peptide amyloid-β (Aβ), found self-assembled in …

… of aggregation of the amyloid-β(25–35) … a β-hairpin conformation, larger aggregates have
extended structures, and a clear transition from compact β-hairpin conformations to extended β-…

… The Amyloid β (Aβ) peptide plays a key role in Alzheimer’s disease (AD), which is an … It is
believed that aggregates of Aβ peptide, misfolded into β-sheet fibrils (so-called “amyloid”) are …

… into supramolecular structures exerting amyloid β-structures. We propose a specified
hypothesis of amyloid formation that describes an at least threefold assembly process from …

Self-assembly of amyloid-β (Aβ) peptides in human brain tissue leads to neurodegeneration in
Alzheimer’s disease (AD). Amyloid … point of Aβ self-assembly. Oligomeric and protofibrillar …

… Self-assembly of amyloid-β (Aβ) peptides has been studied intensively since the initial
identification of Aβ as the primary proteinaceous component of amyloid plaques in Alzheimer’s …

… investigating the self-assembly of peptides based on a core sequence of the amyloid β (Aβ)-…
of hydrophobic and aromatic interactions on peptide self-assembly. In particular, we have …