… Here, we show that different stages of amyloid aggregation can be examined by performing
… microscopy images of heat-denatured β-lactoglobulin fibrils. The atomic force microscopy …

… microscopy (AFM) to examine aggregation of freshly prepared AβP 1–42 and to examine the
role of AβP concentration, imaging … –48 h of real-time AFM imaging (a) in water show only …

… to probe in situ the occurrence of amyloid aggregation in experimental models of disease. …
In a first set of standard confocal fluorescence microscopy experiments we used HiLyte Fluor …

… of scanning probe microscopy (SPM) for imaging biological … a better understanding of the
amyloid aggregation mechanism at the … AFM has been used to study the aggregation and self-…

… , we focus on amyloid studies involving the use of aggregation-… be induced to emit intensely
upon aggregation. The AIE property … Fluorescence microscope imaging of amyloid shape, …

… Statistical investigation of this population over a large series of images shows a minimal
increase in the total number of β-amyloid aggregates (height>1 nm) over time. This is illustrated …

… 42 aggregation with living cells by applying the QD imaging … fluorescence microscopy
confirmed Aβ 42 aggregation imaging … aggregates using a conventional fluorescence microscope (…

… stochastic optical reconstruction microscopy, dSTORM, … microscopy techniques. It is reviewed
later in this chapter in a section headed Super-resolution imaging of amyloid aggregation; …

… amyloid proteins undergo conformational transition and assemble into amyloid aggregate,
with the main focus on amyloid fibril, … microscopy (TEM) images of amyloid fibrils are shown. …

… Representative fluorescence microscopy images of SH-SY5Y cells after 24 h incubation with
(a) medium only, (b) Aβ, (c) 4 μM TS1, (d) 4 μM TS2, (e) 20 μM Aβ and 4 μM TS1, and (f) 20 …