Regulation of androgen receptor levels: implications for prostate cancer progression and therapy
KL Burnstein - Journal of cellular biochemistry, 2005 - Wiley Online Library
… principal androgens, testosterone and dihydrotestosterone (DHT), are mediated via androgen
receptors (ARs), ligand‐activated transcription factors that belong to the nuclear receptor …
receptors (ARs), ligand‐activated transcription factors that belong to the nuclear receptor …
Androgen receptor in prostate cancer
CA Heinlein, C Chang - Endocrine reviews, 2004 - academic.oup.com
… AR remains important in the development and progression of prostate cancer. AR … cancer
progression, and the majority of androgen-independent or hormone refractory prostate cancers …
progression, and the majority of androgen-independent or hormone refractory prostate cancers …
Androgen receptor: a key molecule in the progression of prostate cancer to hormone independence
ME Taplin, SP Balk - Journal of cellular biochemistry, 2004 - Wiley Online Library
… Our present mandate is to apply our knowledge of AR signaling in prostate cancer
progression to the development of more effective therapeutics for prostate cancer patients. …
progression to the development of more effective therapeutics for prostate cancer patients. …
Androgen receptor involvement in the progression of prostate cancer.
H Suzuki, T Ueda, T Ichikawa… - Endocrine-related cancer, 2003 - erc.bioscientifica.com
… of codon 877 mutation in the androgen receptor gene in advanced prostate cancers. …
of the androgen receptor gene and progression of human prostate cancer. Nature Genetics …
of the androgen receptor gene and progression of human prostate cancer. Nature Genetics …
The androgen receptor gene and its influence on the development and progression of prostate cancer
JS Montgomery, DK Price, WD Figg - The Journal of Pathology, 2001 - Wiley Online Library
… of the androgen receptor in prostate cancer. The CAG and GGN trinucleotide repeats in exon
… of the androgen receptor gene have been linked to prostate cancer risk and progression in …
… of the androgen receptor gene have been linked to prostate cancer risk and progression in …
Evolution of the androgen receptor pathway during progression of prostate cancer
PJM Hendriksen, NFJ Dits, K Kokame, A Veldhoven… - Cancer research, 2006 - AACR
… of prostate cancer. We defined the androgen receptor pathway by selecting 200 genes
that were androgen responsive in prostate cancer cell lines and/or xenografts. This …
that were androgen responsive in prostate cancer cell lines and/or xenografts. This …
[HTML][HTML] Androgen receptor signaling in prostate cancer development and progression
PE Lonergan, DJ Tindall - Journal of carcinogenesis, 2011 - ncbi.nlm.nih.gov
… in the progression to CRPC is essential in developing successful future therapies. This
review provides a synopsis of AR structure and signaling in prostate cancer progression, with a …
review provides a synopsis of AR structure and signaling in prostate cancer progression, with a …
The role of androgen receptor mutations in prostate cancer progression
… In such cases androgen receptor … which the receptor is thought to remain active is mutation.
This review summarises the present data on androgen receptor mutations in prostate cancer, …
This review summarises the present data on androgen receptor mutations in prostate cancer, …
Drug insight: role of the androgen receptor in the development and progression of prostate cancer
ME Taplin - Nature Clinical Practice Oncology, 2007 - nature.com
… the 'intracrine' production of androgen Novel approaches to androgen receptor inhibition are
in … through combined inhibition of classic androgen receptor signaling and other interrelated …
in … through combined inhibition of classic androgen receptor signaling and other interrelated …
A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion–resistant growth
Z Guo, X Yang, F Sun, R Jiang, DE Linn, H Chen… - Cancer research, 2009 - AACR
… The androgen receptor (AR) plays a key role in progression to incurable androgen
ablation–resistant prostate cancer (PCA). We have identified three novel AR splice variants lacking …
ablation–resistant prostate cancer (PCA). We have identified three novel AR splice variants lacking …
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