Expression and degradation of androgen receptor: mechanism and clinical implication
DK Lee, C Chang - The Journal of Clinical Endocrinology & …, 2003 - academic.oup.com
… androgens is mediated by androgen receptor (AR), a member of the steroid hormone receptor
… AR to interact with androgen response elements (ARE) in various androgen target genes (…
… AR to interact with androgen response elements (ARE) in various androgen target genes (…
Androgen receptor coregulators in prostate cancer: mechanisms and clinical implications
M Rahman, H Miyamoto, C Chang - Clinical cancer research, 2004 - AACR
The transcriptional activity of androgen receptor (AR) is modulated by coregulators that
have a significant influence on a number of functional properties of AR, including the ligand …
have a significant influence on a number of functional properties of AR, including the ligand …
Androgen receptor variant-driven prostate cancer: clinical implications and therapeutic targeting
ES Antonarakis, AJ Armstrong, SM Dehm… - Prostate cancer and …, 2016 - nature.com
… androgen receptor and androgen receptor splice variants. Full-length androgen receptor
and androgen receptor … Androgen receptor splice variants (AR-Vs) lack the AR ligand-binding …
and androgen receptor … Androgen receptor splice variants (AR-Vs) lack the AR ligand-binding …
[HTML][HTML] Androgen receptor and prostate cancer stem cells: biological mechanisms and clinical implications
Prostate cancer (PCa) contains phenotypically and functionally distinct cells, and this cellular
heterogeneity poses clinical challenges as the distinct cell types likely respond differently …
heterogeneity poses clinical challenges as the distinct cell types likely respond differently …
Androgen receptor function in folliculogenesis and its clinical implication in premature ovarian failure
S Kimura, T Matsumoto, R Matsuyama, H Shiina… - Trends in Endocrinology …, 2007 - cell.com
… An initial step to answering this question is to understand the function of androgen receptors
… of androgens is exerted through transcriptional regulation by the nuclear androgen receptor …
… of androgens is exerted through transcriptional regulation by the nuclear androgen receptor …
Interactions between androgen receptor signaling and other molecular pathways in prostate cancer progression: Current and future clinical implications
C Pisano, M Tucci, RF Di Stefano, F Turco… - Critical reviews in …, 2021 - Elsevier
… Androgen receptor (AR) is considered the main driver in PCa … androgen receptor and other
molecular pahtways in prostate cancer. TKR: tyrosine kinase receptor; AR: androgen receptor…
molecular pahtways in prostate cancer. TKR: tyrosine kinase receptor; AR: androgen receptor…
[HTML][HTML] The role of the androgen receptor in ovarian cancer carcinogenesis and its clinical implications
H Zhu, X Zhu, L Zheng, X Hu, LZ Sun, X Zhu - Oncotarget, 2017 - ncbi.nlm.nih.gov
… We also summarize and discuss key data describing clinical implications in ovarian cancer.
A better understanding on the activity and clinical relevance of the steroid hormone receptor …
A better understanding on the activity and clinical relevance of the steroid hormone receptor …
[HTML][HTML] Clinical implications of androgen-positive triple-negative breast cancer
M Brumec, M Sobočan, I Takač, D Arko - Cancers, 2021 - mdpi.com
… This review summarizes the recent findings of a vast array of studies conducted on androgen
receptor-positive triple-negative breast cancer (AR-positive TNBC) to provide a better …
receptor-positive triple-negative breast cancer (AR-positive TNBC) to provide a better …
Selective androgen receptor modulators: current knowledge and clinical applications
ZJ Solomon, JR Mirabal, DJ Mazur… - Sexual medicine …, 2019 - academic.oup.com
… Selective androgen receptor modulators (SARMs) differentially bind to androgen receptors
depending on each SARM’s chemical structure. As a result, SARMs result in anabolic cellular …
depending on each SARM’s chemical structure. As a result, SARMs result in anabolic cellular …
Androgens: basic biology and clinical implication.
ES Orwoll - Calcified tissue international, 2001 - search.ebscohost.com
… of androgen effects in bone have become more completely understood. The clinical implications
of these androgen … by androgen receptor insensitivity syndromes, androgens appear to …
of these androgen … by androgen receptor insensitivity syndromes, androgens appear to …
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