… Androgen receptor (AR) is a steroid receptor transcriptional factor for testosterone and
dihydrotestosterone consisting of four main domains, the N-terminal domain, DNA-binding domain…

… clinical implications of testing and strategies that may benefit AR splice variant (AR-V)-positive
men and discuss whether such variants are passengers or drivers of aggressive clinical …

… crossing the plasma membrane and binding to the androgen receptor (AR) or via
mechanisms independent of the ligand-dependent transactivation function of nuclear …

… Herein, we will review the accumulating evidence pertaining to AR variant characterization,
biologic properties, emergence in the clinic, and the clinical implications of AR variants in …

… the role of androgen-TH crosstalk in PCa and its implication in clinical management. As life
… of action of androgen receptor and structure of androgen receptor (AR) and thyroid receptor. (…

… Androgens regulate the function of normal prostate cells by activating androgen receptors
(ARs) (Figure 1). These form a complex which is subsequently translocated from the …

… This would have significant clinical implications when we consider the development of AR-…
Details frequent expression of androgen receptor (AR) in breast cancer, and its implication in …

… Phase II trial of bicalutamide in patients with androgen receptor-positive, estrogen receptor-…
Search terms were androgen receptor, androgen, and anti-androgen alone or in combination …

… in codon 877 of the androgen receptor. The mutant receptor loses androgen specificity and
is activated … The discovery of the mutated androgen receptor sheds light on the emergence of …

… of endogenous androgens and related synthetic compounds are believed to be mediated
solely by the androgen receptor (AR; NR3C4). AR is a member of the nuclear receptor (NR) …