Androgen receptor (AR) coregulators: an overview

CA Heinlein, C Chang - Endocrine reviews, 2002 - academic.oup.com
… The biological action of androgens is mediated through the androgen receptor (AR).
Androgen-… The transcriptional activity of AR is affected by coregulators that influence a number of …

Androgen receptor coregulators and their involvement in the development and progression of prostate cancer

R Chmelar, G Buchanan, EF Need… - … Journal of cancer, 2007 - Wiley Online Library
… The androgen receptor signaling axis plays an essential role in … of the AR and associated
coregulators to influence the natural … The androgen receptor (AR) is a member of the nuclear …

Androgen receptor (AR) coregulators: a diversity of functions converging on and regulating the AR transcriptional complex

HV Heemers, DJ Tindall - Endocrine reviews, 2007 - academic.oup.com
… as AR coregulators. In the current review, we provide an overview of the AR coregulators that
… , we propose a classification of AR coregulatory proteins according to their intrinsic primary …

Androgen receptor coregulators in prostate cancer: mechanisms and clinical implications

M Rahman, H Miyamoto, C Chang - Clinical cancer research, 2004 - AACR
… of androgen receptor (AR) is modulated by coregulators that … Because androgens and AR
have pivotal roles in the … cancer progression, these coregulators may significantly modulate the …

Androgen regulation of the androgen receptor coregulators

A Urbanucci, KK Waltering, HE Suikki, MA Helenius… - BMC cancer, 2008 - Springer
… was to identify coregulators whose expression is regulated by either the androgens and/or …
In order to identify AR coregulators whose expression is regulated by androgens, we …

Expression of androgen receptor coregulators in prostate cancer

MJ Linja, KP Porkka, Z Kang, KJ Savinainen… - Clinical Cancer …, 2004 - AACR
coregulators may significantly modify transcriptional activity of AR, suggesting that these
coregulators … Here, our goal was to assess alterations in the expression of the AR coregulators

Androgen receptor coregulators: recruitment via the coactivator binding groove

DJ van de Wijngaart, HJ Dubbink… - Molecular and cellular …, 2012 - Elsevier
androgens testosterone and dihydrotestosterone mediate their effect by binding to, and
activation of the androgen receptor … from where it recruits coregulators to orchestrate chromatin …

Androgen receptor corepressors: an overview

L Wang, CL Hsu, C Chang - The Prostate, 2005 - Wiley Online Library
androgen are mediated by the androgen receptor (AR), a ligand-dependent transcriptional
factor and member of the nuclear receptor (… receptor coregulator in prostate cancer cells. Proc …

Androgen receptor corepressors and prostate cancer

CJ Burd, LM Morey, KE Knudsen - Endocrine-related cancer, 2006 - erc.bioscientifica.com
Androgens regulate numerous physiological … of androgens is mediated through the androgen
receptor (AR), a ligand-dependent transcription factor that belongs to the nuclear receptor

A comprehensive analysis of coregulator recruitment, androgen receptor function and gene expression in prostate cancer

S Liu, S Kumari, Q Hu, D Senapati… - Elife, 2017 - elifesciences.org
… interactions between androgen receptors, coregulators and … one between the androgen
receptor, the coregulator WDR77, … that do not respond to androgen deprivation therapy, where …