… the androgen receptor. We have chosen the term selective androgen receptor modulators
(… used for similar molecules targeting the estrogen receptor. Below we briefly describe the …

… androgen receptor modulators (SARMs) and other tissue-selective nuclear hormone receptor
modulators that activate their cognate receptors … beneficial effects of androgens and other …

… Selective androgen receptor modulators (SARMs) are small molecule drugs that function
as either androgen receptor (AR) agonists or antagonists. Variability in AR regulatory proteins …

… Selective androgen receptor modulators (SARMs) differentially bind to androgen receptors
depending on each SARM’s chemical structure. As a result, SARMs result in anabolic cellular …

The androgens testosterone and dihydrotestosterone play an essential role in the development
and maintenance of primary and secondary male characteristics. Androgens bind to a …

… of other androgen target tissues (eg … androgens are mediated by the androgen receptor
(AR). This ligand-dependent transcription factor belongs to the superfamily of nuclear receptors…

Publisher Summary This chapter examines the different aspects of selective androgen
receptor modulators (SARMS). Testosterone (T) is an endogenous ligand for the androgen …

… The present study aimed to identify selective androgen receptor modulators (SARMs) with
… In the in vitro assays, these compounds demonstrated moderate to high androgen receptor (…

Androgen receptor (AR) plays a critical role in the function of several organs including …
Selective androgen receptor modulators (SARMs) bind to the AR and demonstrate osteo- and myo…

… the androgen receptor (AR), a member of the nuclear receptor superfamily of transcription
factors. Binding of specific ligands to the AR initiates signalling by translocation of the receptor …