… A novel androgen receptor splice variant is upregulated during PCa progression and
promotes androgen depletion-resistant growth. Cancer Research 69 2305–2313. …

… More broadly, AR-V7 is one member of a group of alternatively spliced AR variants that share
… ΔLBD androgen receptor variants have shown the capability to induce androgen receptor-…

… Many of these unconfirmed PSA declines are transient and thus of unclear clinical
significance. The results suggested that treatment-naive mCRPC patients positive for AR-V7 may …

… androgen receptor and androgen receptor splice variants. Full-length androgen receptor and
androgen receptor splice variants … Androgen receptor splice variants (AR-Vs) lack the AR …

… We reported previously that the detection of androgen receptor splice variant-7 (AR-V7)
mRNA in circulating tumor cells (CTCs) correlated with poor outcomes from the use of …

… , C-terminally truncated androgen receptor (AR)-variants. Lacking the … therapies, these
AR-variants (termed ARΔLBD) are … AR-variants and their clinical significance as markers/targets …

Background Detection of androgen receptor splice variant-7 (AR-V7) mRNA in circulating
tumour cells (CTCs) is associated with worse outcome in metastatic castration-resistant …

… [8] Inability of this AR variant to bind DNA is associated with sequestration of the coregulatory
… The findings summarized in the present review have considerable clinical significance. …

… The androgen receptor (AR) is a key prostate cancer drug target. Suppression of AR
signaling mediated by the full-length AR (AR-FL) is the therapeutic goal of all existing AR-directed …

… Androgens mediate the biological effects through the androgen receptor (AR). Given time,
patients with advanced prostate cancer treated with ADT inevitably progress to castration-…