Androgen receptor in prostate cancer

CA Heinlein, C Chang - Endocrine reviews, 2004 - academic.oup.com
… maintenance of the prostate is dependent on androgen acting through the androgen receptor
(AR). AR remains important in the development and progression of prostate cancer. AR …

Androgen receptors in prostate cancer.

Z Culig, H Klocker, G Bartsch… - … -related cancer, 2002 - erc.bioscientifica.com
… Gregory CW, Johnson RTJ, Mohler JL, French FS & Wilson EM 2001b Androgen receptor
stabilization in recurrent prostate cancer is associated with hypersensitivity to low androgen. …

The role of androgens and the androgen receptor in prostate cancer

JD Debes, DJ Tindall - Cancer letters, 2002 - Elsevier
Prostate cancer (PCa) is the leading diagnosed malignancy in men in … androgens and
the androgen receptor (AR) has been studied extensively in PCa. Plasma levels of androgens

Androgen receptors in prostate cancer

Z Culig, H Klocker, G Bartsch, H Steiner… - The Journal of urology, 2003 - Elsevier
… In the last decade research on androgen receptor (AR) in prostate cancer led to … in cancer
tissue and disease outcome. AR binding assays were not routinely used in prostate cancer

Androgen receptors in prostate cancer

JM Bentel, WD Tilley - Journal of endocrinology, 1996 - joe.bioscientifica.com
… function of the prostate gland were elucidated … prostate, prostate cancers were
androgen-responsive and that tumour regression was evident following removal of testicular …

Androgen receptor signaling in prostate cancer

Z Culig, FR Santer - Cancer and Metastasis Reviews, 2014 - Springer
… downregulation of androgen levels in the circulation or blockade of the androgen receptor
(AR… and/or nonsteroidal anti-androgens hydroxyflutamide and bicalutamide are considered for …

Androgen receptor mutations in prostate cancer

M Marcelli, M Ittmann, S Mariani, R Sutherland… - Cancer research, 2000 - AACR
… We analyzed the frequency and relevance of mutations in the coding region of the androgen
receptor (AR) in genomic DNA extracted from 137 specimens of prostate cancer. The …

The androgen receptor in prostate cancer

J Trapman, AO Brinkmann - Pathology-Research and Practice, 1996 - Elsevier
… ceptor in hormone dependent and hormone independent prostate cancer. In this review a …
the androgen receptor, and of androgen receptor structure and expression in prostate cancer. …

[HTML][HTML] Role of androgen receptor in prostate cancer: a review

K Fujita, N Nonomura - The world journal of men's health, 2019 - synapse.koreamed.org
Androgen receptor (AR) is a steroid receptor transcriptional factor for testosterone and …
AR plays pivotal roles in prostate cancer, especially castration-resistant prostate cancer (…

Androgen receptor: structure, role in prostate cancer and drug discovery

MH Tan, J Li, HE Xu, K Melcher, E Yong - Acta Pharmacologica Sinica, 2015 - nature.com
Androgens and androgen receptors (AR) play a pivotal … as androgen insensitivity syndrome
(AIS) and prostate cancer, are associated with alterations in AR functions. Indeed, androgen