Mechanisms of abdominal aortic aneurysm formation
A Daugherty, LA Cassis - Current atherosclerosis reports, 2002 - Springer
… Abdominal aortic aneurysms are permanent dilations of the aorta in the infra-renal region.
However, this simple statement belies a complex issue of defining the prevalence of AAAs. In …
However, this simple statement belies a complex issue of defining the prevalence of AAAs. In …
… , laboratory, and transesophageal echocardiographiccorrelates of thoracic aortic dimensions in the populationwith implications for thoracic aortic aneurysm formation
Y Agmon, BK Khandheria, I Meissner… - Journal of the American …, 2003 - jacc.org
… abdominal aortic aneurysms (thoracoabdominal aneurysms) … limited role in thoracic aortic
dilatation, as also suggested by a … in the thoracic aorta, including complex aortic plaques, are …
dilatation, as also suggested by a … in the thoracic aorta, including complex aortic plaques, are …
MicroRNA-29 in aortic dilation: implications for aneurysm formation
… aneurysm formation, 6 , 12 and age is the major risk factor for abdominal aortic aneurysm
formation… of miR-29 may link aging to aneurysm formation. Therefore, we next studied the role …
formation… of miR-29 may link aging to aneurysm formation. Therefore, we next studied the role …
Aortic aneurysm formation: lessons from human studies and experimental models
MJ Davies - Circulation, 1998 - Am Heart Assoc
… of aortic aneurysm formation. These data suggest that there are additional factors involved in
aortic aneurysm formation. … A very small subgroup of saccular aneurysms are due to genes …
aortic aneurysm formation. … A very small subgroup of saccular aneurysms are due to genes …
Mechanisms of aortic aneurysm formation: translating preclinical studies into clinical therapies
FM Davis, DL Rateri, A Daugherty - Heart, 2014 - heart.bmj.com
… contrast, inhibition of miR-29b reduced aortic dilation in elastase and AngII-induced aortic …
of the pathways that contribute to thoracic aortic aneurysm formation.25 S53 S54 Over the past …
of the pathways that contribute to thoracic aortic aneurysm formation.25 S53 S54 Over the past …
Cellular mechanisms of aortic aneurysm formation
RA Quintana, WR Taylor - Circulation Research, 2019 - Am Heart Assoc
… This loss of structural integrity is key to aortic dilation and rupture. Of interest is that the vast
majority of AAAs occur below the level of the renal arteries, which may reflect the differing …
majority of AAAs occur below the level of the renal arteries, which may reflect the differing …
Pathogenesis of abdominal aortic aneurysm
STR MacSweeney, JT Powell… - British journal of …, 1994 - Wiley Online Library
… The aorta must withstand the huge load imposed by arterial blood pressure for a lifetime; if
it weakens, gradual aneurysmal dilatation occurs over a period of years'". Superimposed on …
it weakens, gradual aneurysmal dilatation occurs over a period of years'". Superimposed on …
[HTML][HTML] Morphologic predictors of aortic dilatation in type B aortic dissection
JL Tolenaar, JW van Keulen, FHW Jonker… - Journal of vascular …, 2013 - Elsevier
… favorable, with significant dilatation of the aorta in 25% within 4 … events, such as aneurysm
formation and aortic rupture, may … the dissection can predict aortic dilatation during follow-up. …
formation and aortic rupture, may … the dissection can predict aortic dilatation during follow-up. …
Development of aortic aneurysm/dilatation during the followup of patients with giant cell arteritis: a cross‐sectional screening of fifty‐four prospectively followed …
A García‐Martínez… - Arthritis Care & …, 2008 - Wiley Online Library
… aortic aneurysm/dilatation among patients with GCA. Our data do not support that aneurysm
formation … or the target tissue may also determine susceptibility to aortic aneurysm/dilatation. …
formation … or the target tissue may also determine susceptibility to aortic aneurysm/dilatation. …
Inhibition of interleukin-1β decreases aneurysm formation and progression in a novel model of thoracic aortic aneurysms
WF Johnston, M Salmon, NH Pope, A Meher, G Su… - Circulation, 2014 - Am Heart Assoc
… TAAs (defined as aortic dilation >50%) existed with aortic dilation of 56.9±6.2% in WT mice
(Figure 1A). WT mice treated with anakinra had significantly reduced aortic dilation at day 14 …
(Figure 1A). WT mice treated with anakinra had significantly reduced aortic dilation at day 14 …
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