The role matrix metalloproteinases in the production of aortic aneurysm

SW Rabkin - Progress in molecular biology and translational …, 2017 - Elsevier
Matrix metalloproteinases (MMPs) have been implicated in the pathogenesis of … aneurysm
because the histology of thoracic aortic aneurysm (TAA) and abdominal aortic aneurysm (AAA…

Matrix metalloproteinase‐2: the forgotten enzyme in aneurysm pathogenesis

M Thompson, G Cockerill - Annals of the New York Academy of …, 2006 - Wiley Online Library
… excessive local concentrations of a number of matrix metalloproteinases (MMP). These MMPs
… of the extracellular matrix that is demonstrated in established and expanding aneurysms. …

[HTML][HTML] Matrix metalloproteinase in abdominal aortic aneurysm and aortic dissection

EM Maguire, SWA Pearce, R Xiao, AY Oo, Q Xiao - Pharmaceuticals, 2019 - mdpi.com
… Tissue sections and blood samples taken from AAA and AD patients have helped
researchers to identify key member of the matrix metalloproteinase (MMP) family, which become …

Vascular extracellular matrix remodeling in cerebral aneurysms

G Bruno, R Todor, I Lewis, D Chyatte - Journal of neurosurgery, 1998 - thejns.org
Matrix metalloproteinases (MMPs) are a homologous … Matrix metalloproteinases, along
with serine proteinases, degrade existing matrix elements and are crucial to extracellular matrix

Urokinase-generated plasmin activates matrix metalloproteinases during aneurysm formation

P Carmeliet, L Moons, R Lijnen, M Baes, V Lemaître… - Nature …, 1997 - nature.com
aneurysm formation remain undefined". Nevertheless, rupture of aortic aneurysms is a major
… Cellular localization of matrix metalloproteinases in the abdominal aortic aneurysm wall. J. …

Role of matrix metalloproteinases in the pathogenesis of intracranial aneurysms

X Zhang, WJ Ares, P Taussky, AF Ducruet… - Neurosurgical focus, 2019 - thejns.org
… Intracranial aneurysms (IAs) are a result of complex … This review explores the role of matrix
metalloproteinases (MMPs) in the … for assessment of aneurysm development and progression. …

Macrophage-derived matrix metalloproteinase-2 and-9 promote the progression of cerebral aneurysms in rats

T Aoki, H Kataoka, M Morimoto, K Nozaki, N Hashimoto - Stroke, 2007 - Am Heart Assoc
… of cerebral aneurysms have not yet been fully understood despite its clinical significance.
Matrix metalloproteinases (… the significance of MMPs in the progression of cerebral aneurysms. …

Matrix metalloproteinases in abdominal aortic aneurysm: characterization, purification, and their possible sources

KM Newmans, AM Malon, RD Shin… - Connective Tissue …, 1994 - Taylor & Francis
… of the matrix metalloproteinase (MMP) … the aneurysmal aortic wall using fluorescence-activated
cell counting revealed a fifty-fold increase in macrophages (a well-known source of matrix

Many faces of matrix metalloproteinases in aortic aneurysms

H Lu, M Aikawa - Arteriosclerosis, thrombosis, and vascular biology, 2015 - Am Heart Assoc
… Schematic summary showing differential effects of matrix metalloproteinase (MMP)-2 …
aneurysms. MMP-2 deficiency in mice infused with AngII leads to disruption of extracellular matrix (…

Role of matrix metalloproteinase inhibitors in preventing abdominal aortic aneurysm

F Aziz, H Kuivaniemi - Annals of vascular surgery, 2007 - Elsevier
… Abdominal aortic aneurysm (AAA) is a significant health problem in the United States, …
matrix metalloproteinases (MMPs) plays a significant role in the destruction of extracellular matrix