… gene expression of renin, angiotensinogen, and angiotensin-converting enzyme (ACE) in
a number of human … per microgram of total RNA, we used a deletion mutant of human renin-…

… sinogen by a proteolytic cleavage catalyzed by renin (EC 3.4.23.15). … These comparisons
established clearly that there is only one gene for human angiotensinogen gene. …

… the genes for human renin and human angiotensinogen … the interaction of human renin
and angiotensinogen with the … for the specific testing of both human genes in rats. Further, the …

… In contrast, a novel orally active human renin inhibitor (HRI), 30 … HRI decreased plasma
human renin activity by 95% and … dTGR harboring human renin and angiotensinogen genes, Ang …

… in the molecular genetics of the renin–angiotensin system genes with a special emphasis
on human hypertension. The renin–angiotensin system consists of four main proteins: (1) …

… RAS (renin and angiotensinogen), including studies done with transgenic animals. We also
refer to a recently published study in which gene targeting of the angiotensinogen gene was …

… both the human renin and human angiotensinogen genes through … human renin or
angiotensinogen genes against a mouse genetic background possessing endogenous angiotensin-…

… for angiotensin II production together with the renin … human genomic library and a human
angio tensinogen cDNA, we recently cloned and sequenced the human angiotensinogen gene.…

… renin activity and angiotensinogen and measured the expression of renin and angiotensinogen
genes in … Methods: Tissue renin activity and tissue levels of angiotensinogen were …

… angiotensin system has been suggested as the most significant pathway of RAS. A genetic
polymorphism in the human gene for the angiotensin-… animal data support angiotensin II to be …