Knock out of the annexin gene OsAnn3 via CRISPR/Cas9-mediated genome editing decreased cold tolerance in rice

C Shen, Z Que, Y Xia, N Tang, D Li, R He… - Journal of Plant Biology, 2017 - Springer
annexin gene OsAnn3 knockout was performed via the CRISPR/Cas9 (clustered regularly
interspaced short palindromic repeats/CRISPR associated proteins) mediated genome editing

miR-196a is able to restore the aggressive phenotype of annexin A1 knock-out in pancreatic cancer cells by CRISPR/Cas9 genome editing

R Belvedere, P Saggese, E Pessolano… - International Journal of …, 2018 - mdpi.com
… Moreover, the establishment of an ANXA1 knock-out (KO) in our in vitro model by CRISPR/Cas9
genome editing system on MIA PaCa-2 PC cells revealed the deregulation of a large …

The rice annexin gene OsAnn5 is involved in cold stress tolerance at the seedling stage

Z Que, Q Lu, Q Li, C Shen - Plant Direct, 2023 - Wiley Online Library
Annexins exist widely in plants as multigene families and … characterization of the rice annexin
gene OsAnn5. The findings … proteins) mediated genome editing resulted in sensitivity to …

A targeting delivery system for effective genome editing in leukemia cells to reverse malignancy

XH Ren, C Xu, LL Li, Y Zuo, D Han, XY He… - Journal of Controlled …, 2022 - Elsevier
… Cell apoptosis was studied by Annexin V-FITC/PI dual staining. The cell cycle, cell migration
and cell adhesion were also studied. Unedited cells treated by CP@PPM were studied for …

Peptide and aptamer decorated delivery system for targeting delivery of Cas9/sgRNA plasmid to mediate antitumor genome editing

BY Liu, XY He, C Xu, XH Ren, RX Zhuo… - ACS applied materials …, 2019 - ACS Publications
… -functionalized gene delivery vector to achieve efficient genome editing in targeted …
genome editing on apoptosis of cancer cells, DS-ANalg-edited HeLa cells stained with Annexin

Genome editing abrogates angiogenesis in vivo

X Huang, G Zhou, W Wu, Y Duan, G Ma, J Song… - Nature …, 2017 - nature.com
… vessels, and that editing of genomic VEGFR2 locus using … This work establishes a strong
foundation for genome editing … establish a strong foundation for genome editing as a novel …

Functional role of annexins in zebrafish caudal fin regeneration–A gene knockdown approach in regenerating tissue

M Quoseena, S Vuppaladadium, S Hussain, S Banu… - Biochimie, 2020 - Elsevier
genome editing method involving the electroporation of CRISPR targets in adult zebrafish.
Annexin genes … The low efficiencies of tissue specific genome editing are the common issues …

Multifunctional vector for delivery of genome editing plasmid targeting β-catenin to remodulate cancer cell properties

XY He, BY Liu, Y Peng, RX Zhuo… - ACS applied materials & …, 2018 - ACS Publications
… delivery of genome editing plasmids to targeted cells is of critical importance in genome
editing. … cell nuclei to mediate genome editing, resulting in an efficacious knockout of CTNNB1 …

[HTML][HTML] Identification of Annexin A4 as a hepatopancreas factor involved in liver cell survival

D Zhang, VS Golubkov, W Han, RG Correa, Y Zhou… - Developmental …, 2014 - Elsevier
… Utilizing mass spectrometry and in vivo assays, we determined the molecular target of 2F11
to be Annexin A4 (Anxa4), a calcium binding protein. We further found that in both zebrafish …

MSC exosome mediated myocardial repair is inhibited by knockdown of Igf-1 signaling pathway through CRISPR/Cas9 genome editing

Y Li, L Shao, Y Zhang, Z Zhang, J Wang, B Lan… - Circulation, 2016 - Am Heart Assoc
… This CRISPR gene editing approach reduced expression of … as assessed by Death ELISA
and Annexin V. Exosome-derived … CRISPR/Cas9 based gene editing approach confirmed that …