… On the basis of comparison of the cellular and temporal expression pattern of lin-14 in
mutants and wild type, we find that lin-28 and lin-4 act antagonistically to regulate lin-14. …

… are suppressed by a lin‐28 null allele. We further show that the LIN‐28 protein level is
upregulated in the lin‐66 mutants … lin‐46 has also been indicated to have a role antagonistic to …

… The antagonism may involve the direct repression of mes-4 and zfp-1 by the synMuv B(R)
genes, or the antagonistic action of mes-4/zfp-1 and the synMuv B(R) genes on a common set …

… lin-28 is also regulated at this stage by lin-4 and lin-14. (B) In the let-7-dependent pathway,
lin-28 … relieves repression of its target lin-41, thereby promoting the execution of L3 cell fates. …

… In NS cells, Lin-28 is downregulated by mir-125 and let-7, allowing processing of pre-let-7 …
of Lin-28 and loss of pre-let-7 processing activity, suggesting that let-7, mir-125 and lin-28 …

… -specific repression of lin-28. We find that, like lin-14, lin-28 is posttranscriptionally repressed
… existing LIN-28 protein, tipping the antagonism between positive and negative regulation of …

… is necessary for the regulation of lin-28, we constructed a lin-28:GFP fusion lacking the 15
nt LCE (see Figure 2). In contrast to the animals carrying the wild-type lin-28:GFP transgene, …

… We used a strain that expresses LIN-28 tagged with GFP in the lin-28(n719) mutant
background (PQ272); the integrated transgene fully rescues lin-28 mutant phenotypes and is …

… The studies leading to the discovery of the Let-7 block by Lin-28 and questions regarding
the … of lin-14 by the antagonistic action of two other heterochronic genes, lin-4 and lin-28 …

… The antagonistic effect of RA on teleocidin or TPA is unlikely to be due to the neutralization
of the two drugs since pretreatment of the cells with RA followed by subsequent washing and …