Mechanisms of resistance to antihuman epidermal growth factor receptor 2 agents in breast cancer

T Mukohara - Cancer science, 2011 - Wiley Online Library
… overexpression of human epidermal growth factor receptor 2 (… insulin-like growth factor-1
receptor, other epidermal growth factor … Specifically, the epidermal growth factor receptor/HER2 …

Current status of antihuman epidermal growth factor receptor 2 therapies: predicting and overcoming herceptin resistance

A Chung, X Cui, W Audeh, A Giuliano - Clinical breast cancer, 2013 - Elsevier
epidermal growth factor-like domain, MUC4 prevents it from binding to herceptin and may
increase phosphorylation of HER2, potentially altering signals sent from the HER2 receptor. …

Antihuman epidermal growth factor receptor 2 monoclonal antibody therapy for breast cancer

DS Leonard, ADK Hill, L Kelly, B Dijkstra… - British journal of …, 2002 - Wiley Online Library
… the human epidermal growth factor receptor HER) … epidermal growth factor receptor EGFR)
family, a group of EGFR tyrosine kinases3 that play an important role in controlling cell growth

… DS‐8201a, a novel antihuman epidermal growth factor receptor 2 antibody–drug conjugate, in tumors with human epidermal growth factor receptor 2 heterogeneity

Y Ogitani, K Hagihara, M Oitate, H Naito… - Cancer …, 2016 - Wiley Online Library
… DS-8201a is a human epidermal growth factor receptor 2 (HER2)-targeting antibody–drug …
The introduction of trastuzumab emtansine (T-DM1), a human epidermal growth factor

Atezolizumab with neoadjuvant antihuman epidermal growth factor receptor 2 therapy and chemotherapy in human epidermal growth factor receptor 2–positive early …

J Huober, CH Barrios, N Niikura, M Jarząb… - Journal of Clinical …, 2022 - ascopubs.org
epidermal growth factor receptor 2 (HER2)–positive early breast cancer. We report the phase
III IMpassion050 primary analysis of neoadjuvant atezolizumab, PH, and chemotherapy in …

Thermodynamic consequences of mutations in vernier zone residues of a humanized anti-human epidermal growth factor receptor murine antibody, 528

K Makabe, T Nakanishi, K Tsumoto, Y Tanaka… - Journal of Biological …, 2008 - ASBMB
… of murine anti-human epidermal growth factor receptor antibody 528 (m528Fv). Grafting of
the CDRs of m528Fv onto a selected framework region of human antibodies, referred to as …

Trastuzumab deruxtecan in antihuman epidermal growth factor receptor 2 treatment–naive patients with human epidermal growth factor receptor 2–low gastric or …

K Yamaguchi, YJ Bang, S Iwasa, N Sugimoto… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE To investigate efficacy and safety of trastuzumab deruxtecan (T-DXd) in human
epidermal growth factor receptor 2 (HER2)–low gastric or gastroesophageal junction (GEJ) …

Humanized versus murine anti-human epidermal growth factor receptor monoclonal antibodies for immunoscintigraphic studies

AAM Morales, J Ducongé, D Alvarez-Ruiz… - Nuclear medicine and …, 2000 - Elsevier
The anti-human epidermal growth factor receptor (EGF-R) humanized antibody h-R3 (IgG 1 ),
which binds to an extracellular domain of EGF-R, was used to evaluate the biodistribution …

… patient prognosis after neoadjuvant chemotherapy plus antihuman epidermal growth factor receptor 2 therapy of human epidermal growth factor receptor 2–positive …

MT van Mackelenbergh, S Loibl, M Untch… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE The achievement of pathologic complete response (pCR) is strongly prognostic
for event-free survival (EFS) and overall survival (OS) in patients with early breast cancer (…

Immunocytochemical localization of human epidermal growth factor/urogastrone in several human tissues.

AG Kasselberg, DN Orth, ME Gray… - … of Histochemistry & …, 1985 - journals.sagepub.com
Epidermal growth factor (EGF) stimulates the growth of many tissues and inhibits
stimulated … We used polyclonal anti-human EGF sera in the peroxidase-antiperoxidase …