过去一年中添加的文章,按日期排序

Cocrystal formulation design of 4-Aminosalicylic acid and isoniazid via spray-drying based on a ternary phase diagram toward simultaneous pulmonary delivery

P Mo, Y Hatanaka, S Furukawa, M Takase… - Powder Technology, 2024 - Elsevier
3 天前 - … Herein, we investigated the potential of cocrystallization principles for use in
developing dry powder inhaler formulations of anti-tuberculosis drugs. We focused on the …

[HTML][HTML] Advances in an In Vitro Tuberculosis Infection Model Using Human Lung Organoids for Host-Directed Therapies

SY Kim, JA Choi, S Choi, KK Kim, CH Song… - PLoS …, 2024 - journals.plos.org
6 天前 - … The emergence of drug-resistant Mycobacterium tuberculosis (M.tb) has led to the
… novel anti-tuberculosis (anti-TB) drugs. Common methods for testing the efficacy of new drugs

Antimicrobial Resistance and Antimicrobial Therapy of Clinically Relevant Bacteria

G Meletis, L Skoura, E Protonotariou - Antibiotics, 2024 - mdpi.com
6 天前 - … Para-Aminosalicylic acid (PAS) is an integral anti-tuberculosis drug which requires
sequential activation by two Mycobacterial compounds. Previous studies have shown that …

Structural reactions, Green Chemistry Solvents, topology surface, Electronic and Biological studies of 4-(dihydroxymethyl) pyridine-2-carbonitrile–Anti-tuberculosis …

D Jebisha, JNC Mishma, VB Jothy, JM Khaled… - Journal of the Indian …, 2024 - Elsevier
7 天前 - … molecules to manage drug-resistant tuberculosis strains. … a fundamental component
in numerous drugs, fungicides, … This research explores the anti-tuberculosis (TB) effects of …

[PDF][PDF] Evaluation of therapeutic effectiveness of antituberculosis injection based on conversion time in drug-resistant tuberculosis

E Oktaviani, K Anggadiredja, L Amalia - Pharmacia, 2024 - pharmacia.pensoft.net
7 天前 - Drug-resistant tuberculosis is a condition in which Mycobacterium … anti-tuberculosis
drugs, namely isoniazid and rifampicin, which are the two most effective anti-tuberculosis

Clofazimine inhibits innate immunity against Mycobacterium tuberculosis by NF-κB

X Li, X Luo, B Wang, L Fu, X Chen, Y Lu - mSphere, 2024 - journals.asm.org
7 天前 - … consider the immunomodulatory effects of various drugs. In this study, we preliminarily
evaluated the effects of commonly used anti-tuberculosis drugs on innate immunity at the …

Discovery of Novel Pyrimidinetrione Derivatives as Dpre1 Inhibitors with Potent Antimycobacterial Activities

J Liang, Y Liu, Q Guan, Y Li, MZ Zheng… - Available at SSRN … - papers.ssrn.com
7 天前 - … of existing anti-tuberculosis drugs, such as a small range of available drug options,
poor … It is extremely urgent to develop novel anti-tuberculosis drugs. DprE1 is a potential anti-…

Natural deep eutectic solvent for the simultaneous derivatization and microextraction of isoniazid from human plasma

D Meshcheva, F Krekhova, A Shishov, A Bulatov - Analytica Chimica Acta, 2024 - Elsevier
7 天前 - … Isoniazid is a first-line anti-tuberculosis drug that has interindividual variability in
its metabolic processing, leading to significant differences in plasma concentrations among …

Biological and Computational Studies of Hydrazone based Transition Metal (II) Complexes

B Kumar, J Devi, A Dubey, M Kumar - Chemistry & Biodiversity - Wiley Online Library
8 天前 - … blue assay was performed to examine the compounds anti-tuberculosis effectiveness
against the H37Rv strain, with the objective of identifying a potent anti-tuberculosis drug. …

Efficacy and safety of first-line anti-tuberculosis drugs combined with Linezolid for the treatment of pediatric tuberculous meningitis in real-word practice

T Ai, L Jiang, QB Liu, Y Bai, Y Yang… - Zhonghua er ke za … - pubmed.ncbi.nlm.nih.gov
8 天前 - [Efficacy and safety of first-line anti-tuberculosis drugs combined with Linezolid for
the treatment of pediatric tuberculous meningitis in real-word practice] [Efficacy and safety of …