[HTML][HTML] Evaluation of a standardized treatment regimen of anti-tuberculosis drugs for patients with multi-drug-resistant tuberculosis (STREAM): study protocol for a …

AJ Nunn, ID Rusen, A Van Deun, G Torrea… - Trials, 2014 - Springer
… to add new drugs if one or more drugs are withdrawn … anti-tuberculosis drugs, they may
discontinue treatment unnecessarily, re-introduce drugs with suboptimal timing, add new drugs

Severe hepatotoxicity due to anti-tuberculosis drugs in Spain

JR Tost, R Vidal, J Cayla… - … of Tuberculosis and …, 2005 - ingentaconnect.com
… It has been estimated that in Spain anti-tuberculosis drugs … with hepatotoxicity due to
antituberculosis drugs are varied: … anti-tuberculosis drugs, association with other hepatotoxic …

Development of new anti-tuberculosis drug candidates

R Shi, I Sugawara - The Tohoku Journal of experimental medicine, 2010 - jstage.jst.go.jp
… to be effective against antituberculosis drug-resistant strains. … about eight new antituberculosis
drug candidates and describes … of drug-resistance induced by these drug candidates. …

Optimizing treatment outcome of first-line anti-tuberculosis drugs: the role of therapeutic drug monitoring

RK Verbeeck, G Günther, D Kibuule, C Hunter… - European journal of …, 2016 - Springer
… -TB drugs may lead to the development of multidrug resistant and extensively drug resistant
TB… anti-TB drugs is further exacerbated by co-morbidities such as HIV infection and diabetes. …

Biochemical manifestations of anti-tuberculosis drugs induced hepatotoxicity and the effect of silymarin

SA Tasduq, K Peerzada, S Koul, R Bhat, RK Johri - Hepatology research, 2005 - Elsevier
In the present study, the biochemical manifestations of liver toxicity caused by co-administration
of anti-TB drugs, rifampicin (RIF), isoniazid (INH) and pyrazinamide (PZA), in a sub-…

A new evolutionary and pharmacokinetic–pharmacodynamic scenario for rapid emergence of resistance to single and multiple anti-tuberculosis drugs

JG Pasipanodya, T Gumbo - Current opinion in pharmacology, 2011 - Elsevier
… of anti-tuberculosis drug resistance has been shaped by the history of development of
anti-tuberculosis drugsDrug resistance in Mycobacterium tuberculosis was shown to be related to …

Targeting MmpL3 for anti-tuberculosis drug development

JR Bolla - Biochemical Society Transactions, 2020 - portlandpress.com
… to address bottlenecks in drug development, drug repurposing of approved drugs is being
Drug-repurposing strategies can be used to identify new anti-TB drug candidates that have …

Adverse reactions of antituberculosis drugs in hospitalized patients: incidence, severity and risk factors

MR Javadi, G Shalviri, K Gholami… - … and drug safety, 2007 - Wiley Online Library
… to anti-tuberculosis (anti-TB) drug therapy. Objectives To assess the incidence and severity
of adverse drug reactions (ADRs) induced by anti-TB drugs… anti-TB drugs during the research …

[HTML][HTML] Mycobacterium tuberculosis Shikimate Pathway Enzymes as Targets for the Rational Design of Anti-Tuberculosis Drugs

JES Nunes, MA Duque, TF de Freitas, L Galina… - Molecules, 2020 - mdpi.com
… measures and the increase of drug-resistant M. tuberculosis … targets for the development
of new drugs to treat TB. This … be potentially explored towards selective drug development. …

Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol

L Zhang, Y Zhao, Y Gao, L Wu, R Gao, Q Zhang… - Science, 2020 - science.org
… are recognized as targets for the anti-tuberculosis drug ethambutol. In this study… Most
drug-resistant mutations are located near the … and the development of new anti-tuberculosis