Overview of anti-tuberculosis (TB) drugs and their resistance mechanisms
R Shi, N Itagaki, I Sugawara - Mini reviews in medicinal …, 2007 - ingentaconnect.com
… resistance can also develop through alterations or overexpression of the INH drug target
InhA, and 0 to 5% of INH-resistant M. tuberculosis isolates have mutations in the inhA open …
InhA, and 0 to 5% of INH-resistant M. tuberculosis isolates have mutations in the inhA open …
Novel solid forms of the anti-tuberculosis drug, Isoniazid: Ternary and polymorphic cocrystals
… We also report ternary cocrystals of INH, INH·NA·SA and INH·NA·FA. All the solid forms
are thoroughly characterized by spectroscopic, X-ray diffraction and thermal techniques. In …
are thoroughly characterized by spectroscopic, X-ray diffraction and thermal techniques. In …
Anti-tuberculosis activity of lipophilic isoniazid derivatives and their interactions with first-line anti-tuberculosis drugs
T Parumasivam, HSN Kumar, P Ibrahim… - journal of pharmacy …, 2013 - Elsevier
… for synthesis of INH-C16, INH-C17 and INH-C18 respectively, followed by … INH-C16,
INH-C17 and INH-C18 were chemically synthesized by augmenting the amine side chain of INH …
INH-C17 and INH-C18 were chemically synthesized by augmenting the amine side chain of INH …
Towards a new tuberculosis drug: pyridomycin–nature's isoniazid
… anti‐tuberculosis agent isoniazid. However, most interestingly, no cross resistance was
observed between pyridomycin and isoniazid, … most frequently encountered isoniazid‐resistant …
observed between pyridomycin and isoniazid, … most frequently encountered isoniazid‐resistant …
Rifampicin-resistant Mycobacterium tuberculosis: susceptibility to isoniazid and other anti-tuberculosis drugs
EV Kurbatova, JS Cavanaugh, NS Shah… - … of tuberculosis and …, 2012 - ingentaconnect.com
… RMP-resistant TB, INH susceptibility may correlate with susceptibility to other antituberculosis
drugs, and this knowledge might help in planning more effective treatment regimens. Our …
drugs, and this knowledge might help in planning more effective treatment regimens. Our …
Eco-friendly disposal of expired anti-tuberculosis drug isoniazid and its role in the protection of metal
… Isoniazid with different 5-substituted indole-3-carboxaldehyde. Thus, this study offers eco-friendly
and economical disposal of expired drug isoniazid … earlier studied isoniazid derivatives …
and economical disposal of expired drug isoniazid … earlier studied isoniazid derivatives …
[HTML][HTML] Computational approach to understanding the mechanism of action of isoniazid, an anti-TB drug
L Jena, P Waghmare, S Kashikar, S Kumar… - International journal of …, 2014 - Elsevier
… This INH intermediate in the presence of NADH forms INH-NAD adduct which inhibits inhA
(… Isoniazid is used in conjunction with other effective anti-tuberculosis agents under multi-drug …
(… Isoniazid is used in conjunction with other effective anti-tuberculosis agents under multi-drug …
Isoniazid metal complex reactivity and insights for a novel anti-tuberculosis drug design
EHS Sousa, LA Basso, DS Santos… - JBIC Journal of …, 2012 - Springer
… Here, we investigated the reactivity of isoniazid metal complexes as prototypes for novel
self… isoniazid or (isoniazid)pentacyanoferrate(II) complex resulted in similar oxidized isoniazid …
self… isoniazid or (isoniazid)pentacyanoferrate(II) complex resulted in similar oxidized isoniazid …
Docking and molecular dynamic study of isoniazid derivatives as anti-tuberculosis drug candidate
R Mardianingrum, SRN Endah, E Suhardiana… - Chemical Data …, 2021 - Elsevier
… ppm, isoniazid derivatives with an MIC of 6.9 μM, and the N-(Disubstitutedbenzoyl)Isoniazid …
So, recently we have designed and computational study some isoniazid derivatives to be …
So, recently we have designed and computational study some isoniazid derivatives to be …
Cucurbituril-resisted acylation of the anti-tuberculosis drug isoniazid via a supramolecular strategy
H Cong, CR Li, SF Xue, Z Tao, QJ Zhu… - Organic & biomolecular …, 2011 - pubs.rsc.org
… isoniazid (INH) and the chemical structures of INH, cucurbiturils Q[6] and Q[7], acetyl coenzyme
A and acylating agents. … thioester groups that are used to convey the acetyl group to INH. …
A and acylating agents. … thioester groups that are used to convey the acetyl group to INH. …
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