[HTML][HTML] Novel targets to develop new antibacterial agents and novel alternatives to antibacterial agents
TM Belete - Human Microbiome Journal, 2019 - Elsevier
… Even if there have been several studies done over the last decade to discover novel
antibacterial agents by inhibiting the new targets the results have not come up to expectation. The …
antibacterial agents by inhibiting the new targets the results have not come up to expectation. The …
New aminoacyl-tRNA synthetase inhibitors as antibacterial agents
J Pohlmann, H Brotz-Oesterhelt - Current Drug Targets …, 2004 - ingentaconnect.com
… inhibits any of the aa-RS is a potential antibacterial agent. The clinical utility of this principle
is proven by the natural product Ile-RS inhibitor … RS inhibitors and their antibacterial potential …
is proven by the natural product Ile-RS inhibitor … RS inhibitors and their antibacterial potential …
Recent advances in inhibitors of bacterial fatty acid synthesis type II (FASII) system enzymes as potential antibacterial agents
Y Wang, S Ma - ChemMedChem, 2013 - Wiley Online Library
… the discovery of antibacterial agents with new mechanisms of … inhibitors of bacterial FASII as
potential antibacterial agents, … those inhibitors that mainly target β-ketoacyl-ACP synthase, β-…
potential antibacterial agents, … those inhibitors that mainly target β-ketoacyl-ACP synthase, β-…
Antibacterial agents specifically inhibiting lipopolysaccharide synthesis
R Goldman, W Kohlbrenner, P Lartey, A Pernet - Nature, 1987 - nature.com
… In conclusion, peptide prodrugs of compound III represent antibacterial agents which … the
case and suggested that its antibacterial action was due to inhibition of fatty acid biosynthesis (K…
case and suggested that its antibacterial action was due to inhibition of fatty acid biosynthesis (K…
Prospects for aminoacyl-tRNA synthetase inhibitors as new antimicrobial agents
JG Hurdle, AJ O'Neill, I Chopra - Antimicrobial agents and …, 2005 - Am Soc Microbiol
… This situation is driving the search for novel antibacterial agents that inhibit targets that are
… to current chemotherapeutic agents (18, 19). In this regard, the aminoacyl-tRNA synthetase (…
… to current chemotherapeutic agents (18, 19). In this regard, the aminoacyl-tRNA synthetase (…
[PDF][PDF] New targets for antibacterial agents
FA Amer, EM El-Behedy, HA Mohtady - Biotechnology and Molecular …, 2008 - academia.edu
… for the design of new antibacterial agents. Such agents may prove beneficial for immunocom-…
approaches to obtain novel anthranilic acid acyl carrier protein synthase inhibitors. J. Med. …
approaches to obtain novel anthranilic acid acyl carrier protein synthase inhibitors. J. Med. …
Antibacterial agents
R Oiwa - The search for bioactive compounds from …, 1992 - Springer
… The selective toxicity of a therapeutic agent should be superior to avoid … inhibitors of bacterial
cell wall biosynthesis were detected by various screening methods. A penicillinase inhibitor …
cell wall biosynthesis were detected by various screening methods. A penicillinase inhibitor …
Modes of action of antibacterial agents
DG Allison, PA Lambert - Molecular medical microbiology, 2024 - Elsevier
… The mechanism of inhibition involves binding the antibiotic to a cysteine residue of the
enzyme [5], [6], [7]. Fosfomycin appears to inhibit the enzyme selectively because other reactions …
enzyme [5], [6], [7]. Fosfomycin appears to inhibit the enzyme selectively because other reactions …
Tyrosyl-tRNA synthetase inhibitors as antibacterial agents: Synthesis, molecular docking and structure–activity relationship analysis of 3-aryl-4-arylaminofuran-2 (5H) …
ZP Xiao, TW Ma, ML Liao, YT Feng, XC Peng… - European journal of …, 2011 - Elsevier
… To learn more about the structure–antibacterial activity … inhibitors and antibacterial agents.
The results show that some of the synthesized compounds exhibit excellent antibacterial …
The results show that some of the synthesized compounds exhibit excellent antibacterial …
The targets of currently used antibacterial agents: lessons for drug discovery
RP Lange, HH Locher, PC Wyss… - Current pharmaceutical …, 2007 - ingentaconnect.com
… Intriguingly, growth inhibition or even complete loss of … elicited upon treatment with an
antibacterial agent. In addition, their … antibacterial agents, including anti-mycobacterial agents, is …
antibacterial agent. In addition, their … antibacterial agents, including anti-mycobacterial agents, is …
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