What's new in antibiotic resistance? Focus on beta-lactamases
M Babic, AM Hujer, RA Bonomo - Drug resistance updates, 2006 - Elsevier
… Integrons are genetic elements of variable length that contain a 5′ conserved integrase
gene (int), gene cassettes with other antibiotic resistance genes, and an integration site for the …
gene (int), gene cassettes with other antibiotic resistance genes, and an integration site for the …
β-Lactam antibiotic resistance: a current structural perspective
MS Wilke, AL Lovering, NCJ Strynadka - Current opinion in microbiology, 2005 - Elsevier
… The β-lactamases confer significant antibiotic resistance to their bacterial hosts by hydrolysis
of the amide bond of the four-membered β-lactam ring. These enzymes are especially …
of the amide bond of the four-membered β-lactam ring. These enzymes are especially …
Molecular basis of antibiotic resistance and β-lactamase inhibition by mechanism-based inactivators: perspectives and future directions
C Therrien, RC Levesque - FEMS microbiology reviews, 2000 - academic.oup.com
… classes of antibiotics, could … of resistance to the future generation of β-lactams by bacteria
is inevitable and therefore much care must be taken in the way we use β-lactam antibiotics in …
is inevitable and therefore much care must be taken in the way we use β-lactam antibiotics in …
New definitions of extended‐spectrum β‐lactamase conferring worldwide emerging antibiotic resistance
… .1, 2 Three of six dangerous pathogens are antibiotic-resistant Gram-negative pathogens. …
resistance is that severe clinical problems arise from the emergence of antibiotic resistance …
resistance is that severe clinical problems arise from the emergence of antibiotic resistance …
Resistance to β-lactam antibiotics
K Poole - Cellular and Molecular Life Sciences CMLS, 2004 - Springer
… resistance mechanisms include the development of novel β-lactamase-stable β-lactams,
β-lactamase inhibitors to be employed with existing β-lactams, β-lactam compounds that bind …
β-lactamase inhibitors to be employed with existing β-lactams, β-lactam compounds that bind …
CTX-M-type β-lactamases: a successful story of antibiotic resistance
MM D'Andrea, F Arena, L Pallecchi… - International Journal of …, 2013 - Elsevier
Production of extended-spectrum β-lactamases (ESBLs) is the principal mechanism of
resistance to oxyimino-cephalosporins evolved by members of the family Enterobacteriaceae. …
resistance to oxyimino-cephalosporins evolved by members of the family Enterobacteriaceae. …
Aspergillomarasmine A overcomes metallo-β-lactamase antibiotic resistance
… β-lactam antibiotic such as meropenem as we show here, resistance can be overcome and
antibiotic … AMA (or semi-) is therefore an excellent lead for an antibiotic adjuvant co-therapy to …
antibiotic … AMA (or semi-) is therefore an excellent lead for an antibiotic adjuvant co-therapy to …
[PDF][PDF] A review on β-lactam antibiotic drug resistance
UU Zango, M Ibrahim, SAA Shawai… - MOJ Drug Des …, 2019 - researchgate.net
… the effect of β-lactamases. This review discussed the mechanism of β-lactam antibiotic
activity, the mechanisms of β-lactam antibiotic resistance and how to overcome the effect of the β-…
activity, the mechanisms of β-lactam antibiotic resistance and how to overcome the effect of the β-…
Metallo-β-lactamases: novel weaponry for antibiotic resistance in bacteria
MW Crowder, J Spencer, AJ Vila - Accounts of chemical research, 2006 - ACS Publications
… The most prevalent resistance mechanism is the expression of enzymes tailored to
hydrolyze these antibiotics, namely, β-lactamases. Most β-lactamases possess an essential Ser …
hydrolyze these antibiotics, namely, β-lactamases. Most β-lactamases possess an essential Ser …
[HTML][HTML] Antibiotic resistance and extended spectrum beta-lactamases: Types, epidemiology and treatment
… Antibiotic resistance is a problem of deep scientific concern both in hospital and community
settings. Rapid detection in clinical laboratories is essential for the judicious recognition of …
settings. Rapid detection in clinical laboratories is essential for the judicious recognition of …
相关搜索
- antibiotic resistance β lactamase inhibition
- mechanisms of resistance β lactams
- endemic carbapenem resistance beta lactamase
- metallo β lactamases
- extended spectrum β lactamases
- escherichia coli β lactamase
- threat of antibiotic resistance β lactams
- beta lactamases evaluation of antibiotic resistance
- β lactam antibiotics bacterial resistance
- development of β lactam antibiotics
- eskape pathogens β lactam resistance
- β lactam antibiotics medicinal chemistry perspective
- global trends β lactam resistance
- β lactam antimicrobial resistance with focus
- β lactam antibiotic targets
- ceftazidime avibactam β lactam resistance