… , it is unclear whether cellular responses to antibiotics have a similar protective role. By …
coli to four antibiotics, we found that trimethoprim induces a rapid acid stress response that …

… In the present study, acid stress caused increased sensitivity toward 4 antibiotics, but it
also increased C. sakazakii resistance toward 8 others (with variable strain response toward …

… in an acidic environment showed decreased resistance to most of the tested antibiotics, …
decreased 2- to 8-fold after acid stress. The resistance decreased in CPI during exposure to …

… of antibiotics in the acidic environment, we pre-incubated the antibiotics in physiologically
neutral pH 7.5 or acidic pH … to highly stressful antibiotic treatments, while acidic pH significantly …

… regulating the size of membrane channels in an acidic environment [77]. Additionally, the …
from acidic conditions [79]. Interestingly, the acid stress response is stimulated by antibiotics, …

… thiol-associated stress response; therefore, we hypothesized that AC2P36 may disrupt the
bacterium's redox poise and sensitize Mtb to the sulfhydryl oxidizer diamide or the antibiotics …

… and latently hostile environments. This hypothesis is in line with the finding that bacterial
killing—not only by antibiotics but also by environmental hazards such as acid stress, toxic …

… antibiotic resistance in Escherichia coli was investigated using mutants with deletions of genes
known to be involved in antibiotic … antibiotic in combination with environmental conditions. …

… compounds but also by the seemingly unrelated salicylic acid, menadione, and others. To
assess whether activation of mar in otherwise antibiotic sensitive cells affects pH i , we treated …

… To induce DNA damage we used the antibiotic nalidixic acid … proton homeostasis in more
acidic environments. Buffering the … stress is removed or the bacterium succumbs to the stress. …