Pharmacokinetics and pharmacodynamics of antibiotics in cystic fibrosis: a narrative review

E Castagnola, G Cangemi, A Mesini… - International journal of …, 2021 - Elsevier
… This narrative review aimed to summarise what is known to date about the PK/PD … commonly
used antibiotics to treat recurrent respiratory infections in CF patients. The literature was …

Systematic review of antistaphylococcal antibiotic therapy in cystic fibrosis

K McCaffery, RE Olver, M Franklin, S Mukhopadhyay - Thorax, 1999 - thorax.bmj.com
… treatment in cystic fibrosis is precluded by trial heterogeneity, our systematic review
supports the hypothesis that antistaphylococcal treatment in cystic fibrosis achieves increased …

Inhaled antibiotics for stable non-cystic fibrosis bronchiectasis: a systematic review

AM Brodt, E Stovold, L Zhang - European Respiratory Journal, 2014 - Eur Respiratory Soc
… This systematic review suggests that inhaled antibiotics have an acceptable safety profile.
Bronchospasm was the most common adverse event, occurring in 10% of patients treated with …

Pulmonary rehabilitation for cystic fibrosis: A narrative review of current literature

EI Kalamara, ET Ballas, G Pitsiou… - Monaldi Archives for …, 2021 - monaldi-archives.org
Pulmonary rehabilitation is a key component in cystic fibrosis care. This review summarizes
… Macrolide antibiotics and the risk of cardiac arrhythmias. Am J Respir Crit Care Med 2014;…

[HTML][HTML] Efficacy and Safety of Dry Powder Antibiotics: A Narrative Review

D de la Rosa-Carrillo, G Suárez-Cuartín… - Journal of Clinical …, 2023 - mdpi.com
… The use of inhaled antibiotics was initially almost exclusively confined to patients with
cystic fibrosis (CF). However, it has been extended in recent decades to patients with non-CF …

[HTML][HTML] Cystic fibrosis: recent insights into inhaled antibiotic treatment and future perspectives

G Taccetti, M Francalanci, G Pizzamiglio, B Messore… - Antibiotics, 2021 - mdpi.com
… A systematic literature review and in-depth Bayesian network meta-analysis was carried out
… clinical evidence regarding the use of inhaled antibiotics for the management of chronic P. …

Inhaled antibiotics for pulmonary exacerbations in cystic fibrosis

S Smith, NJ Rowbotham… - … of Systematic Reviews, 2022 - cochranelibrary.com
… To determine if treatment of pulmonary exacerbations with inhaled antibiotics in people
with cystic fibrosis improves their quality of life, reduces time off school or work, and improves …

[HTML][HTML] Antibiotic resistance in patients with cystic fibrosis: past, present, and future

EP Perikleous, D Gkentzi, A Bertzouanis, E Paraskakis… - Antibiotics, 2023 - mdpi.com
… Moreover, features linked to modified pharmaco-kinetics and pulmonary parenchyma
penetration make the dosing of antibiotics even more challenging. In this review, we present the …

[HTML][HTML] Inhaled corticosteroids in adults with non-cystic fibrosis bronchiectasis: from bench to bedside. A narrative review

MÁ Martínez-García, G Oscullo, A García-Ortega… - Drugs, 2022 - Springer
… However, there is little evidence for their use in non-cystic fibrosis bronchiectasis (hereafter, …
This manuscript aims to review the basic properties of ICSs, how they impact bronchiectasis …

[HTML][HTML] Challenges in the diagnosis and management of bacterial lung infections in solid organ recipients: a narrative review

M Carugati, LC Morlacchi, AM Peri, L Alagna… - International Journal of …, 2020 - mdpi.com
… Though well intended, overuse of antibiotics contributes to … In this review, we discuss the
above factors which contribute … This is particularly relevant in the setting of cystic fibrosis lung …